Precise Measured GFR for Preclinical Studies
- Validated Fluorescent Tracer Agents
- Capture Longitudinal Measurements
- Animal Not Restrained During Monitoring
- Minature Detection Device for Use in All Animals
- Transdermal, No Labor-Intensive Sampling Required
Successful Use in Nephrology Research
MediBeacon technology is used by leading medical schools, academic centers, research institutes, and pharmaceutical companies worldwide to enhance preclinical assessment of kidney therapeutics, evaluate nephrotoxicity, and gain fundamental understanding of kidney function in animals.
Research using the MediBeacon preclinical product has been featured in numerous posters presented at previous American Society of Nephrology (ASN) Kidney Week meetings. In all there are over 65 published studies in which this transdermal mGFR technique was used (peer reviewed and conference abstracts).
Preclinical Device – Technical Specifications
The instrument contains light emitting diodes capable of exciting the fluorescent tracer agent and a photodiode that collects the emission light.
After amplification and digitization, the data sets are either stored in the internal memory of the microcontroller (available for mice and rats), or are transmitted to a host computer in real-time (only available for rats). When using the integrated storage the dataset is transferred to a PC via a USB connection for display and analysis.