Fluorescent tracer agents coupled with transdermal detection technology enable physiological monitoring.
Bright fluorescent agents designed not to interact with the body are sensed through the skin.
New clinical applications for fluorescent tracer agent-based systems are in development.
Clinical and preclinical studies are underway to advance the use of fluorescence to measure and monitor disease progression.
Composition of matter, algorithm, and method patents are a platform for continued innovation.
Leading academic centers, research institutes, contract research organizations and pharmaceutical companies worldwide rely on MediBeacon technology.
Clinically practical solutions which can reduce the cost of healthcare while improving the standard of care are the goal.
Fluorescent agents engineered to not interact with the body have the potential to enable measurement and monitoring of vital organ systems.
Measurement of GFR is widely accepted as the best indicator of kidney function. A clinically practical and accurate real-time point of care methodology holds promise.
Increased intestinal permeability is implicated in inflammatory bowel disease. Rapid assessment of gut barrier function is a focus.
Fluorescent agent angiography has the potential to aid in diagnosis and monitoring of vasculature leakage seen in Diabetic Retinopathy, Macular Degeneration and Retinal Vasculitis.
Intraoperative identification of ureter or ureteral injury is critical to prevent serious complications. Use of fluorescent agents could potentially aid in surgical visualization.
Potential medical applications for fluorescent tracer agent-based systems are wide ranging and target important unmet patient needs.
Technology whose development began inside leading medical technology companies is nearing human application today.
Industry leaders including scientists and clinicians are behind fluorescence enabled technology that has the potential to impact global health.
Investment in fluorescence-based systems target multiple multi-billion dollar unmet medical needs.
Our approach to quality concentrates on the integrity of processes and preventive measures.
The latest developments are global in scope.
When using the devices for measurements in mice (standard measuring time of 1 hour) a trained person can comfortably manage 4-5 devices in parallel. To explain further, setting up 4-5 measurements one after the other takes about 1 hour so the first measurement is ready when the last one is started thus enabling high throughput. The device used for the first measurement can be read out on the PC and then immediately be used for a subsequent measurement on another animal.
Below you will find links to tutorial video articles which have been published in the Journal of Visualized Experiments.
Technique used in mice: https://www.jove.com/t/58520/transdermal-measurement-of-glomerular-filtration-rate-in-mice
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*MediBeacon products are in various stages of clinical development and are not yet approved for human use.
**The Transdermal GFR Measurement System (TGFR) is intended to measure Glomerular Filtration Rate (GFR) in patients with impaired or normal renal function. References on this website to measured kidney function and measured renal function refer to the measured GFR.