GASTROENTEROLOGY
Advances in fluorescent technology brought to light.
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MediBeacon Gastroenterology Program
Focus is on GI permeability to transform management of autoimmune and inflammatory diseases

CLINICAL PROGRAM
First in-human clinical studies are underway to establish the feasibility of fluorescent tracer agent-based systems to quantify the permeability of the gastrointestinal tract in patients with active Crohn’s Disease.*

GI PUBLICATIONS
MediBeacon gut permeability research is being completed in collaboration with researchers at the Mayo Clinic and at Washington University in St. Louis. Results of initial preclinical invivo work has been presented at Digestive Disease Week and published in the online Nature Publication – Scientific Reports.

In the US IBD care costs
as much as
$32B
ANNUALLY
– The American Journal of Managed Care, Foram Mehta., Economic implications of inflammatory bowel disease and its management, March 2016
Growing Research Interest
Peer-reviewed publications on the topic have increased to >1,000 annually in 2018.
– PubMed entries on “intestinal permeability,” 1970-2018
FUNDING FROM THE BILL & MELINDA GATES FOUNDATION
Washington University School of Medicine, in collaboration with MediBeacon has received Grand Challenges Explorations and Grand Challenges Explorations Phase II grants totaling over $1 million. Grand Challenges Explorations is an initiative funded by the Bill & Melinda Gates Foundation.