It is true that the mice are more active and this is not a problem for the measurements. The devices are actually used more frequently in mice than in rats. This is due to the limited blood volume of mice when blood sampling is necessary. This is especially true when GFR is to be measured in the same animal consecutively in short intervals. With our technique the same animal can be measured on a daily basis, as no blood sampling is required.

Of course, attachment of the Preclinical MX device is a bit trickier in mice compared to rats in regard to size and activity of the animals. Therefore, Zoom training on the handling of the Preclinical MX device in mice is offered to the customer. Generally, it takes a week or two of training until the customers get the system running stable in their labs when working with mice.

Removal of the Preclinical MX devices can be done without any anesthesia in both rats and mice. For mice the easiest way to do this is placing them on the cage lid offering the animals support whilst quickly removing the patch and tape.