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Transdermal Detection of MB-102 and Correlation to Meropenem Pharmacokinetics During Continuous Renal Replacement Therapy: In Vivo Results
Monday, May 8th, 2023
Richard B. Dorshow, James R. Johnson, Jeng-Jong Shieh, I. Rochelle Riley, Thomas E. Rogers, Christopher J. Pino, Kimberly A. Johnston, Peter Tang, Thomas D. Nolin,
Adsorption and Clearance of the Novel Fluorescent Tracer Agent MB-102 During Continuous Renal Replacement Therapy: In Vitro Results
Monday, May 8th, 2023
Soo M. Jang Jeng-Jong Shieh, Ivan R. Riley, Richard B. Dorshow, and Bruce A. Mueller, “Adsorption and Clearance of the Novel Fluorescent Tracer Agent MB-102
Novel Chiral High-Performance Liquid Chromatographic (HPLC) Determination of MB-102, A New Fluorescent Tracer Agent Enabling the Measurement of Point-of-Care Glomerular Filtration Rate
Wednesday, August 3rd, 2022
Jeng-Jong Shieh, I. Rochelle Riley, Thomas E. Rogers, and Richard B. Dorshow, “Novel Chiral High-Performance Liquid Chromatographic (HPLC) Determination of MB-102, A New Fluorescent Tracer
Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of Glomerular Filtration Rate
Wednesday, July 13th, 2022
Joseph E. Bugaj, Richard B. Dorshow, “Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of
Absence of developmental or reproductive toxicity in rats for MB-102, a fluorescent tracer agent for point-of-care measurement of glomerular filtration rate
Friday, April 15th, 2022
Joseph E. Bugaj , Richard B. Dorshow, “Absence of developmental or reproductive toxicity in rats for MB-102, a fluorescent tracer agent for point-of-care measurement of
Effectiveness of MB-102, a novel fluorescent tracer agent, for conducting ocular angiography in dogs
Friday, May 15th, 2020
Christopher G. Pirie, Thomas E. Rogers, Richard B. Dorshow, “Effectiveness of MB-102, a novel fluorescent tracer agent, for conducting ocular angiography in dogs,” American Journal
Characterization of MB-102, a New Fluorescent Tracer Agent for Point-of-Care Renal Function Monitoring
Sunday, January 12th, 2020
Jeng-Jong Shieh, I. Rochelle Riley, Thomas E. Rogers, Lung-Fa Kao, Richard B. Dorshow, “Characterization of MB-102, a New Fluorescent Tracer Agent for Point-of-Care Renal Function
Next tier in vitro and in vivo nonclinical studies further elucidating the safety and toxicity profile of MB-102, a novel fluorescent tracer agent for measurement of glomerular filtration rate
Friday, January 10th, 2020
Richard B. Dorshow, Joseph E. Bugaj, “Next tier in vitro and in vivo nonclinical studies further elucidating the safety and toxicity profile of MB-102, a
Transdermal fluorescence detection of a dual fluorophore system for noninvasive point-of-care gastrointestinal permeability measurement
Thursday, January 9th, 2020
Richard B. Dorshow, J. R. Johnson, Martin P. Debreczeny, I. Rochelle Riley, Jeng-Jong Shieh, Thomas E. Rogers, Carla Hall-Moore, Nurmohammad Shaikh, L. Colleen Rouggly-Nickless, and
Clinical analysis and quantitation of MB-102, a novel fluorescence tracer agent, in human plasma
Tuesday, January 7th, 2020
Jeng-Jong Shieh, Rochelle Riley, Richard B. Dorshow, “Clinical analysis and quantitation of MB-102, a novel fluorescence tracer agent, in human plasma,” The Royal Society of
Transdermal optical renal function monitoring in humans: development, verification, and validation of a prototype device
Saturday, January 4th, 2020
Martin P. Debreczeny, Richard B. Dorshow, “Transdermal optical renal function monitoring in humans: development, verification, and validation of a prototype device,” Journal of Biomedical Optics,
Measurement of gut permeability using fluorescent tracer agent technology
Wednesday, January 1st, 2020
Richard B. Dorshow, Carla Hall-Moore, Nurmohammad Shaikh, Michael R. Talcott, William A. Faubion, Thomas E. Rogers, Jeng Jong Shieh, Martin P. Debreczeny, James R. Johnson,
Pre-clinical toxicity evaluation of MB-102, a novel fluorescent tracer agent for real-time measurement of glomerular filtration rate
Friday, December 27th, 2019
Joseph E. Bugaj, Richard B. Dorshow, “Pre-clinical toxicity evaluation of MB-102, a novel fluorescent tracer agent for real-time measurement of glomerular filtration rate,” Regulatory Toxicology
Exogenous fluorescent tracer agents based on pegylated pyrazine dyes for real-time point-of-care measurement of glomerular filtration rate
Friday, December 20th, 2019
A.R. Poreddy, W.L. Neumann, J.N. Freskos, R. Rajagopalan, B. Asmelash, K.R. Gaston, R.M. Fitch, K.P. Galen, J.J. Shieh, and R.B. Dorshow, “Exogenous fluorescent tracer agents
Hydrophilic pyrazine dyes as exogenous fluorescent tracer agents for real-time point-of-care measurement of glomerular filtration rate
Tuesday, December 17th, 2019
R. Rajagopalan, W.L. Neumann, A.R. Poreddy, R.M. Fitch, J.N. Freskos, B. Asmelash, K.R. Gaston, K.P. Galen, J.J. Shieh, and R.B. Dorshow, “Hydrophilic pyrazine dyes as
A highly efficient method for the N-alkylation of amino pyrazines: synthesis of hydrophilic red fluorescent dyes
Monday, December 16th, 2019
A.R. Poreddy, B. Asmelash, W.L. Neumann, and R.B. Dorshow, “A highly efficient method for the N-alkylation of amino pyrazines: synthesis of hydrophilic red fluorescent dyes,”
Fluorescence-enhanced Europium-Diethylenetriaminepentaacetic (DTPA)-Monoamide complexes for the Assessment of Renal Function
Friday, December 13th, 2019
L.K. Chinen, K.P. Galen, K.T. Kuan, M.E. Dyszlewski, H. Ozaki, H. Sawai, R.S. Pandurangi, F.G. Jacobs, R.B. Dorshow, and R. Rajagopalan, “Fluorescence-enhanced Europium-Diethylenetriaminepentaacetic (DTPA)-Monoamide complexes

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*MediBeacon products are in various stages of clinical development and are not yet approved for human use.

**The Transdermal GFR Measurement System (TGFR) is intended to measure Glomerular Filtration Rate (GFR) in patients with impaired or normal renal function. References on this website to measured kidney function and measured renal function refer to the measured GFR.

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