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Blood pressure-independent renoprotective effects of small interference RNA targeting liver angiotensinogen in experimental diabetes
Thursday, September 22nd, 2022
Edwyn O. Cruz-López, Liwei Ren,Estrellita Uijl, Marian C. Clahsen-van Groningen, Richard van Veghel, Ingrid M. Garrelds, Oliver Domenig, Marko Poglitsch, Ivan Zlatev, Timothy Rooney, Anne
Intravital imaging of hemodynamic glomerular effects of enalapril or/and empagliflozin in STZ-diabetic mice
Thursday, September 15th, 2022
Hannah Kroeger, Friederike Kessel, Jan Sradnick, Vladimir Todorov, Florian Gembardt, Christian Hugo, “Intravital imaging of hemodynamic glomerular effects of enalapril or/and empagliflozin in STZ-diabetic mice”,
Influence of carnosine and carnosinase-1 on diabetes-induced afferent arteriole vasodilation: implications for glomerular hemodynamics
Monday, June 6th, 2022
Angelica Rodriguez-Niño, Diego O. Pastene*, Steffen A. Hettler, Jiedong Qiu, Thomas Albrecht, Srishti Vajpayee, Rossana Perciaccante, Norbert Gretz, Stephan J.L. Bakker, Bernhard K. Krämer, Benito
Glucosidase Inhibitor Alleviates Inflammation and Fibrosis in Type-1 Diabetic Kidney
Monday, April 11th, 2022
Subir Kumar Juin, Sathnur Pushpakumar, Utpal Sen, “Glucosidase Inhibitor Alleviates Inflammation and Fibrosis in Type-1 Diabetic Kidney”, Experimental Biology 2022 Poster abstract 564.9.
Investigating the influence of the gut microbiome on diabetic renal disease
Monday, April 11th, 2022
Jiaojiao Xu, Jason Sanchez, Kunal Gupta, Jennifer Pluznick, “Investigating the influence of the gut microbiome on diabetic renal disease”, Experimental Biology 2022 Poster abstract 564.7.
Effects of Combination of RTA nh404 and Dapagliflozin on Renal Involvement and Body Composition in Experimental Rat Model of Diabetic Kidney Disease
Thursday, February 24th, 2022
Fukami, K, Ota, K, Kodama, G, Yokota, Y, Shinohara, M, Ito, S, “Effects of Combination of RTA nh404 and Dapagliflozin on Renal Involvement and Body
Mechanism of the Canagliflozin-Induced Early Decline in GFR in Obese Diabetic Rats
Thursday, February 24th, 2022
Kodama, G, Kaida, Y, Ito, S, Ohta, K, Yokota, Y, Shinohara, M, Fukami, K, “Mechanism of the Canagliflozin-Induced Early Decline in GFR in Obese Diabetic
Salt loading with unilateral nephrectomy accelerates decline in glomerular filtration rate in the hypertensive, obese, type 2 diabetic SDT fatty rat model of diabetic kidney disease
Thursday, February 3rd, 2022
Yuichi Shinozaki, Yuko Katayama, Fuminari Yamaguchi, Tomohisa Suzuki, Kana Watanabe, Kinuko Uno, Takahiro Tsutsui, Miki Sugimoto, Masami Shinohara, Katsuhiro Miyajima, Takeshi Ohta, “Salt loading with
Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models
Tuesday, December 28th, 2021
Philipp Tauber, Frederick Sinha, Raffaela S. Berger, Wolfram Gronwald, Katja Dettmer, Michaela Kuhn, Maximilian Trum, Lars S. Maier, Stefan Wagner, Frank Schwed, “Empagliflozin Reduces Renal
Loss of renal olfactory receptor 1393 leads to improved glucose homeostasis in a type 1 diabetic mouse model
Thursday, December 9th, 2021
Alexis R. Schiazza, Elizabeth G. Considine, Madison Betcher, Blythe D. Shepard, ” Loss of renal olfactory receptor 1393 leads to improved glucose homeostasis in a
The Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone Improves Left Ventricular Function in Preclinical Diabetic CKD
Tuesday, November 16th, 2021
Ixchel Q. Lima Posada, Yohan Stephan, Matthieu Soulié, Benjamin Bonnard, Roberto Palacios Ramirez, Lionel Nicol, Peter Kolkhof, Paul Mulder, Frederic Jaisser, “The Nonsteroidal Mineralocorticoid Receptor
SGLT-2 Inhibition Ameliorates Tubular Injury with Metabolic Suppression in Very Early Phase of Diet-Induced Diabetic Kidney Disease
Tuesday, November 16th, 2021
Hiroshi Maekawa, Dorian Kaminski, Margaret E. Fain, Biliana Marcheva, Susan E. Quaggin, “SGLT-2 Inhibition Ameliorates Tubular Injury with Metabolic Suppression in Very Early Phase of
Hypertensive Diabetic Kidney Disease Increases the Severity of Experimental AKI
Tuesday, November 16th, 2021
Anna Menshikh, Rachel Delgado, Maya Brewer, Min Yang, Chris R. Kennedy, Haichun Yang, Mark P. de Caestecker, “Hypertensive Diabetic Kidney Disease Increases the Severity of
Loss of Functional SCO2 Attenuates Oxidative Stress in Diabetic Kidney Disease
Saturday, October 30th, 2021
Nehaben A. Gujarati, Alexandra R. Leonardo, Jessica M. Vasquez, Yiqing Guo, Bismark O. Frimpong, Elbek Fozilov, Monica P. Revelo, Ilse S. Daehn, John C. He,
Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease
Thursday, July 29th, 2021
Mette V. Østergaard, Thomas Secher, Michael Christensen, Casper Gravesen Salinas, Urmas Roostalu, Jacob Lercke Skytte, Ida Rune, Henrik H. Hansen, Jacob Jelsing, Niels Vrang, and
The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)
Thursday, June 24th, 2021
Aowen Zhuang1, Felicia Y. T. Yap, Danielle J. Borg, Domenica McCarthy, Amelia Fotheringham, Sherman Leung, Sally A. Penfold, Karly C. Sourris, Melinda T. Coughlan, Benjamin
Dual Blockade of Endothelin a Receptor (ETA) and Sodium-Glucose Cotransporter 2 (SGLT2) to Prevent Diabetic Kidney Disease Progression on a Type 2 Murine Model
Monday, June 21st, 2021
Ander Vergara Arana, Mireia Molina, Conxita Jacobs Cacha, Pamela Dominguez, Begona Benito, Irene Agraz Daniel Seron Micas, Marıa Jose´ Soler, “Dual Blockade of Endothelin a
Glomerular hyperfiltration with hyperglycemia in the spontaneously diabetic Torii (SDT) fatty rat, an obese type 2 diabetic model
Wednesday, March 24th, 2021
R Sano, Y Ishii, M Yamanaka, Y Yasui, Y Kemmochi, F Kuroki, M Sugimoto, S Fukuda, T Sasase, K Miyajima, D Nakae, T Ohta, “Glomerular
Glomerular hyperfiltration with hyperglycemia in the Spontaneously Diabetic Torii (SDT) fatty rat, an obese type 2 diabetic model
Monday, January 25th, 2021
Ryuhei Sano, Yukihito Ishi, Masao Yamanaka1, Yuzo Yasui, Yusuke Kemmochi, Fuko Kuroki, Miki Sugimoto, Sumiaki Fukuda, Tomohiko Sasase, Katsuhiro Miyajima, Dai Nakae, Takeshi Ohta, “Glomerular
Drug Testing for Residual Progression of Diabetic Kidney Disease in Mice Beyond Therapy with Metformin, Ramipril, and Empagliflozin
Monday, July 13th, 2020
Manga Motrapu, Monika Katarzyna Swiderska, Irene Mesas, Julian Aurelio Marschner, Yutian Lei, Laura Martinez Valenzuela, Jia Fu, Kyung Lee, Maria Lucia Angelotti, Giulia Antonelli, Paola
The Effects of Chronic Dapagliflozin Treatment on the Renal Microvasculature in a Rat Model of Type 2 Diabetes
Wednesday, June 10th, 2020
Connie Ow, Vijayakumar Sukumaran, Jennifer Ngo, Cheng Kun Du, Akihiro Fujiwara, Hirotsugu Tsuchimochi, Hiroshi Hosoda, Roger Evans, James Pearson, “The Effects of Chronic Dapagliflozin Treatment
Revisiting Experimental Models of Diabetic Nephropathy
Tuesday, June 2nd, 2020
Anna Giralt-López, Mireia Molina-Van den Bosch, Ander Vergara, Clara García-Carro, Daniel Seron, Conxita Jacobs-Cachá, and Maria José Soler, “Revisiting Experimental Models of Diabetic Nephropathy,” International
Rodent models of diabetic kidney disease: human translatability and preclinical validity
Monday, May 18th, 2020
Frederikke E. Sembach, Mette V. Østergaard, Niels Vrang, Bo Feldt-Rasmussen, Keld Fosgerau, Jacob Jelsing, Lisbeth N. Fink, “Rodent models of diabetic kidney disease: human translatability
Elucidating the Mechanism for Renal Olfactory Receptor 1393’s Attenuated Type 1 Diabetic Phenotype
Friday, April 24th, 2020
Elizabeth G. Considine Alexis R. Schiazza Blythe D. Shepard, “Elucidating the Mechanism for Renal Olfactory Receptor 1393’s Attenuated Type 1 Diabetic Phenotype.” Federation of American
Soluble (pro)renin receptor treats metabolic syndrome in mice with diet-induced obesity via interaction with PPARγ
Wednesday, April 15th, 2020
Fei Wang, Renfei Luo, Chang-Jiang Zou, Shiying Xie, Kexin Peng, Long Zhao, Kevin T. Yang, Chuanming Xu, and Tianxin Yang, “Soluble (pro)renin receptor treats metabolic
Impact of choice of kinetic model for the determination of transcutaneous FITC‐sinistrin clearance in rats with streptozotocin‐induced type 1 diabetes
Wednesday, March 18th, 2020
Md Mahbub Ullah, Connie P.C. Ow Roger G. Evans, Lucinda M. Hilliard Krause, “Impact of choice of kinetic model for the determination of transcutaneous FITC‐sinistrin
Liraglutide treatment improves the coronary microcirculation in insulin resistant Zucker obese rats on a high salt diet
Friday, February 28th, 2020
Vijayakumar Sukumaran, Hirotsugu Tsuchimochi, Takashi Sonobe, Mark T. Waddingham, Mikiyasu Shirai and James T. Pearson, “Liraglutide treatment improves the coronary microcirculation in insulin resistant Zucker
Effect of Canagliflozin on Glomerular Hyperfiltration Evaluated by Transcutaneous GFR Monitor in Spontaneously Diabetic Torii Fatty Rats
Thursday, January 16th, 2020
Goh Kodama, Yosuke Nakayama, Sakuya Ito, Yunosuke Yokota, Kei Fukami, “Effect of Canagliflozin on Glomerular Hyperfiltration Evaluated by Transcutaneous GFR Monitor in Spontaneously Diabetic Torii
Elevated Podocyte DAAM2 Expression in Diabetic Nephropathy
Tuesday, January 14th, 2020
Chenyang Qi, Haichun Yang, Raymond C. Harris, Agnes B. Fogo, “Elevated Podocyte DAAM2 Expression in Diabetic Nephropathy,” Am. Soc. Nephrol. Kidney Week Abstract Supplement: FR-PO192
Empagliflozin as an Add-On to Linagliptin Ameliorates Renal Interstitial Fibrosis in Spontaneously Diabetic Torii Fatty Rats
Monday, January 13th, 2020
Goh Kodama, Yosuke Nakayama, Sakuya Ito, Yunosuke Yokota, Yusuke Kaida, Kei Fukami, “Empagliflozin as an Add-On to Linagliptin Ameliorates Renal Interstitial Fibrosis in Spontaneously Diabetic
Glycogen synthase kinases 3-α/β inhibition attenuates progression of diabetic kidney disease beyond treatment with metformin/Ramipril/empagliflozin
Thursday, January 9th, 2020
Lidia Anguiano Gómez Manga Motrapu Julian Marschner Hans-Joachim Anders, “NGlycogen synthase kinases 3-α/β inhibition attenuates progression of diabetic kidney disease beyond treatment with metformin/Ramipril/empagliflozin,” Nephrology
GSK3-α/β Inhibition Attenuates Progression of CKD in Lepr-/- Mice with Type 2 Diabetes (T2D) Beyond Standard-of-Care Therapy (SOC) with Metformin/Ramipril/Empagliflozin
Wednesday, January 8th, 2020
Motrapu Manga, Lidia Anguiano-Gomez, Maria Lucia Angelotti, Paola Romagnani, Hans J. Anders, “SK3-α/β Inhibition Attenuates Progression of CKD in Lepr-/- Mice with Type 2 Diabetes
Nephropathy in diabetic db/db mice is accelerated by high protein diet and improved by the SGLT2 inhibitor dapagliflozin
Thursday, December 26th, 2019
Sisse Andersen Nørgaard, François Briand, Fredrik Wolfhagen Sand, Elisabeth Douglas Galsgaard, Henrik Søndergaard, Dorte Bratbo Sørensen, Thierry Sulpice, “Nephropathy in diabetic db/db mice is accelerated
Rapid Progression of Glomerulosclerosis due to Concurrent Diabetes and Hypertension Correlates with Podocyte Damage Shown by Expansion Microscopy
Tuesday, December 17th, 2019
Yalcin Kuzay, Euan Clark, Sara Medina Balbuena, Benito Yard, John Mullins, Wilhelm Kriz, Hermann-Josef Gröne, Sigrid C. Hoffmann, “Rapid Progression of Glomerulosclerosis due to Concurrent
Renal Olfactory Receptor 1393 Contributes to the Development and Progression of Type 1 Diabetes
Saturday, December 14th, 2019
Alexis R. Schiazza, Elizabeth G. Considine, Blythe D. Shepard, “Renal Olfactory Receptor 1393 Contributes to the Development and Progression of Type 1 Diabetes,” Am. Soc.
Restricted Access Matching Human Unilateral AKI, a Reverse Translational Approach to Investigate Kidney Recovery after Ischemia
Friday, December 13th, 2019
Danielle E. Soranno, Hyo-Wook Gil, Lara Kirkbride-Romeo, Christopher Altmann, John R. Montford, Haichun Yang, Ani Levine, Jane Buchanan and Sarah Faubel, “Restricted Access Matching Human
Whole-Kidney 3D Imaging and Transcriptome Assessment in the UNxdb/db Mouse Model of Diabetic Nephropathy
Wednesday, December 4th, 2019
Diabetic Nephropathy Frederikke E. Sembach, Brandon B. Boland, Lisbeth N. Fink, Urmas Roostalu, Jacob L. Skytte, Thomas Secher, Keld Fosgerau, Niels Vrang, Jacob Jelsing, Jacob
The Absence of the ACE N-Domain Decreases Renal Inflammation and Facilitates Sodium Excretion during Diabetic Kidney Disease
Tuesday, December 3rd, 2019
Masahiro Eriguchi, Ellen A. Bernstein, Luciana C. Veiras, Zakir Khan, Duo Yao Cao, Sebastien Fuchs, Alicia A. McDonough, Jorge E. Toblli, Romer A. Gonzalez-Villalobos, Kenneth
Compensatory mechanisms for methylglyoxal detoxification in experimental & clinical diabetes
Tuesday, November 26th, 2019
Dagmar Schumacher, Jakob Morgenstern, Yoko Oguchi, Nadine Volk, Stefan Kopf, Jan Benedikt Groener, Peter Paul Nawroth, Thomas Fleming, Marc Freichel, “Compensatory mechanisms for methylglyoxal detoxification
Dapagliflozin Reduces Glomerular Hyperfiltration and Improves Urine Parameters in db/db Mice on High Protein Diet: A 4-week Model of Diabetic Nephropathy
Monday, November 25th, 2019
Francois Briand, Sisse A. Nørgaard, Noémie Burr, Clément Costard, Emmanuel Brousseau, Nourdine Faresse, Fredrik Wolfhagen Sand, Thierry Sulpice, “Dapagliflozin Reduces Glomerular Hyperfiltration and Improves Urine
Glomerular Injury and Progressive Cardiac Dysfunction in the Obese ZSF1 Rat, a New Model of Diabetic Nephropathy and Heart Failure with Preserved Ejection Fraction
Thursday, November 14th, 2019
Elyse Di marco, Erik Michaëlsson, Charlotte Ericson, Margareta Behrendt, Maria Stromstedt, Magnus Soderberg, Johannes Wikstrom, Anna Granqvist, “Glomerular Injury and Progressive Cardiac Dysfunction in the
Losartan improves renal function and pathology in obese ZSF-1 rats
Friday, November 8th, 2019
Zhi Su, Deborah Widomski, Artur Nikkel, Laura Lets, Marian Namovic, Diana Donnelly-Roberts, Murall Gopalakrishnan, Steve McGaraughty, “Losartan improves renal function and pathology in obese ZSF-1
Renal Olfactory Receptor 1393 Contributes to the Progression of Type II Diabetes in a Diet-Induced Obesity Model
Wednesday, October 30th, 2019
Blythe D Shepard, Hermann Koepsell, and Jennifer L. Pluznick, “Renal Olfactory Receptor 1393 Contributes to the Progression of Type II Diabetes in a Diet-Induced Obesity
An integrin antagonist (MK-0429) decreases proteinuria and renal fibrosis in the ZSF1 rat diabetic nephropathy model
Sunday, October 13th, 2019
Xiaoyan Zhou, Ji Zhang, Robin Haimbach, Wei Zhu, Rosemary Mayer-Ezell, Margarita Garcia-Calvo, Elizabeth Smith, Olga Price, Yanquig Kan, Emanuel Zycband, Yonghua Zhu, Maarten Hoek, Jason
Renal Olfactory Receptor 1393 May Contribute to the Progression of Diabetic Nephropathy
Saturday, October 5th, 2019
Blythe D. Shepard and Jennifer L. Pluznick, “Renal Olfactory Receptor 1393 May Contribute to the Progression of Diabetic Nephropathy,” The FASEB Journal April 2017, vol.
Renal Tubular ACE-Mediated Tubular Injury is The Major Contributor to Microalbuminuria in Early Diabetic Nephropathy
Friday, October 4th, 2019
Masahiro Eriguchi, Mercury Lin, Michifumi Yamashita, Tuantuan V. Zhao, Zakir Khan, Ellen A. Bernstein, Susan B Gurley, Romer A. Gonzalez-Villalobos, Kenneth E. Bernstein, Jorge Fernando
Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes
Tuesday, October 1st, 2019
Micheal S. Ward, Nicole B. Flemming, Linda A. Gallo, Amelia K. Fotheringham, Domenica A. McCarthy, Aowen Zhuang, Peter H. Tang, Danielle J. Borg1, Hannah Shaw,
Transcutaneous Measurement of Glomerular Filtration Rate in a Mouse Model of Diabetic Kidney Disease
Sunday, September 29th, 2019
Asim B. Dey, Leah L. Porras, Shannon M. Harlan, Josef G. Heuer, Mark Kowala, Matthew D. Breyer, Mark Rekhter, “Transcutaneous Measurement of Glomerular Filtration Rate
Longitudinal Characterization of Glomerular Filtration Rate of the Naïve ZSF1 Rat
Tuesday, September 17th, 2019
Haimbach R.E., Ma L-J, Hoek M., Pinto S., Zhou X., “Longitudinal Characterization of Glomerular Filtration Rate of the Naïve ZSF1 Rat,” J. Am. Soc. Nephrol.
Maternal glucose intolerance reduces offspring nephron endowment and increases glomerular volume in adult offspring
Monday, September 16th, 2019
Hokke S., Arias N., Armitage J.A., Puelles V.G., Fong K., Geraci S., Gretz N., Bertram J.F., Cullen-McEwen L.A., “Maternal glucose intolerance reduces offspring nephron endowment
Maternal Glucose Intolerance Reduces Offspring Nephron Endowment and Increases Glomerular Volume in Adult Offspring
Saturday, September 14th, 2019
Hokke S, Arias N, Armitage JA, Puelles VG, Fong K, Geraci S, Gretz N, Bertram JF, Cullen-McEwen LA, “Maternal Glucose Intolerance Reduces Offspring Nephron Endowment
Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice
Tuesday, September 10th, 2019
Gallo LA, Ward MS, Fotheringham AK, Zhuang A, Borg DJ, Flemming NB, Harvie BM, Kinneally TL, Yeh SM, McCarthy DA, Koepsell H, Vallon V, Pollock
PBI-4425, A novel anti-inflamantory/fibrotic compound, improves kidney function and glomerular integrity in the diabetic DB/DB mouse mode
Sunday, September 8th, 2019
Lyne Gagnon, Kathy Hince, François Sarra-Bournet, Liette Gervais, Alexandra Felton, Alexandre Laverdure, William Gagnon, Martin Leduc, Lilianne Geerts, Pierre Laurin, Brigitte Grouix, “PBI-4425, A novel
Longitudinal Changes in Measured Glomerular Filtration Rate, Renal Fibrosis and Biomarkers in a Rat Model of Type 2 Diabetic Nephropathy
Sunday, September 8th, 2019
Su Z. · Widomski D. · Ma J. · Namovic M. · Nikkel A. · Leys L. · Olson L. · Salte K. ·Donnelly-Roberts D.
A Potent Pan-AMPK Activator Improves Renal Structure and Function in the ZSF-1 Rat Model of Diabetic Nephropathy
Friday, September 6th, 2019
Hoek M., Zhou X., Haimbach R. E., Muise E., Ma L-J, Price O., Forrest G.M., Herath K., Zycband E., Ruben Z., Zhu Y., Pinto S.,
Renal Olfactory Receptor 1393 Contributes to Glucose Reabsorption
Thursday, September 5th, 2019
Shepard B. D., Cheval L., Zita P. L., Firestein S., Koepsel H., Doucet A., Pluznick J. L., “Renal Olfactory Receptor 1393 Contributes to Glucose Reabsorption,”
Renal Tubular ACE Affects Microalbuminuria in Early Diabetic Nephropathy
Wednesday, September 4th, 2019
Eriguchi M., Giani J.F., Lin M.Y., Zhao T., Khan Z., Bernstein E.A., Shen X., Gonzalez-Villalobos R.A., Bernstein K.E., “Renal Tubular ACE Affects Microalbuminuria in Early
Vascular Actions of AT1 Angiotensin Receptors Do Not Contribute to Albuminuria or Hyperfiltration in Diabetic Kidney Disease
Wednesday, August 28th, 2019
Sparks M. A., Johnson S. A., Gurley S. B., Thomas M. Coffman T M., “Vascular Actions of AT1 Angiotensin Receptors Do Not Contribute to Albuminuria
A Longitudinal Study on Kidney Function, Pathology, and Multiple Urinary Biomarkers in ZSF1 Rat Model of Type II Diabetic Nephropathy
Wednesday, August 21st, 2019
Z. Su, D. Widomski, M. T. Namovic, D. L. Donnelly‑Roberts, L. Leys, K. Salte, A. L. Nikkel, L. Olson, J. Ma, T. A.Esbenshade, S. McGaraughty,
Losartan improves renal function and pathology in a rat model of type II diabetic nephropathy
Wednesday, August 7th, 2019
Widomski D, Leys L, Larson K, McGaraughty S, Su Z, Nikkel AL, “Losartan improves renal function and pathology in a rat model of type II