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Role of Megalin and Sex in AKI-CKD Transition due to Cardiorenal Syndrome Type 1
Tuesday, November 16th, 2021
Yoshio Funahashi, Jessica F. Hebert, Kevin G. Burfeind, Adam C. Munhall, Megan N. Nickerson, Tahnee Groat, Michael Hutchens, “Role of Megalin and Sex in AKI-CKD
Cilastatin Inhibits Renal Myoglobin Endocytosis and AKI Following Rhabdomyolysis
Tuesday, November 16th, 2021
Jessica F. Hebert, Kevin G. Burfeind, Megan N. Nickerson, Yoshio Funahashi, Mahaba B. Eiwaz, Tahnee Groat, Michael Hutchens, “Cilastatin Inhibits Renal Myoglobin Endocytosis and AKI
Pharmacological Validation of HDAC8 as a Therapeutic Target for AKI
Tuesday, November 16th, 2021
Donna M. Huryn, Keith E. Long, Michael D. McDaniels, Rachel Delgado, Zoe Vaughn,Prema C. Iyer, Veronika Sander, Alan J. Davidson, Mark P. de Caestecker, Neil
UBE-1099, a Novel Non-Covalent Keap1-Nrf2 Inhibitor, Protects Against Renal Ischemia-Reperfusion Injury via Nrf2 Activation
Tuesday, November 16th, 2021
Sayaka Ogi, Hidetoshi Sunamoto, Hirohiko Fukiya, Futoshi Nara, Kazuhiro Onuma, “UBE-1099, a Novel Non-Covalent Keap1-Nrf2 Inhibitor, Protects Against Renal Ischemia-Reperfusion Injury via Nrf2 Activation”, Am.
Regression of Severe Preexisting Glomerular Pathology in a Mouse FSGS Model in Response to Treatment with Macula Densa-Derived Biologicals
Tuesday, November 16th, 2021
Georgina Gyarmati, Urvi Nikhil Shroff, Audrey Izuhara, Janos Peti-Peterdi, “Regression of Severe Preexisting Glomerular Pathology in a Mouse FSGS Model in Response to Treatment with
The Nonsteroidal Mineralocorticoid Receptor Antagonist Finerenone Improves Left Ventricular Function in Preclinical Diabetic CKD
Tuesday, November 16th, 2021
Ixchel Q. Lima Posada, Yohan Stephan, Matthieu Soulié, Benjamin Bonnard, Roberto Palacios Ramirez, Lionel Nicol, Peter Kolkhof, Paul Mulder, Frederic Jaisser, “The Nonsteroidal Mineralocorticoid Receptor
Dexamethasone Attenuates Kidney Ischemia Reperfusion Injury in SD Rats by Mediating M1 Macrophage Cytokine Production
Tuesday, November 16th, 2021
Nataliya Skrypnyk, Henriette Frikke-Schmidt, David W. Frederick, Kamal Albarazanji, Gavin Lewis, Jianying Liu, Lili Guo, Qiu Li, Raul Camacho, Li-Jun Ma, Andrea R. Nawrocki, George
Sparsentan, the Dual Endothelin Angiotensin Receptor Antagonist (DEARA), Improves Kidney Function and Life Span and Protects Against Hearing Loss in Alport Mice with Developed Renal Structural Changes
Tuesday, November 16th, 2021
Dominic E. Cosgrove, MichaelAnne Gratton, Daniel T. Meehan, Denise Vosik, Jacob D. Madison, Duane C. Delimont, Gina C. Samuelson, Diana Jarocki, Radko Komers, Celia P.
Comparison of Imaging Approaches for Quantifying Total Kidney Volume (TKV) and Fibrosis in a Mouse Model of Polycystic Kidney Disease (PKD)
Tuesday, November 16th, 2021
Caroline R. Sussman, Heather L. Holmes, Ka Thao, Adriana Gregory, Ryan J. Meloche, Yaman G. Mkhaimer, Harrison H. Wells, Slobodan Macura, Peter C. Harris, Timothy
SGLT-2 Inhibition Ameliorates Tubular Injury with Metabolic Suppression in Very Early Phase of Diet-Induced Diabetic Kidney Disease
Tuesday, November 16th, 2021
Hiroshi Maekawa, Dorian Kaminski, Margaret E. Fain, Biliana Marcheva, Susan E. Quaggin, “SGLT-2 Inhibition Ameliorates Tubular Injury with Metabolic Suppression in Very Early Phase of
Transdermal Glomerular Filtration Rate Measurement in Conscious Pigs Using the Novel Fluorescent Tracer Agent Relmapirazin
Tuesday, November 16th, 2021
Sabine Neudecker, Daniel Schock-Kusch, Jochen Friedemann, Marlene Jostock, Yury Shulhevich, Dzmitry Stsepankou, Jesse Ross-Jones, James R. Johnson, Thomas E. Rogers, Ivan R. Riley, Jeng-Jong Shieh,
Renal Papillary Function and Repair After Reversible Ureteral Obstruction
Tuesday, November 16th, 2021
Mark P. de Caestecker, Rachel Delgado, Maya Brewer, Min Yang, Haichun Yang, “Renal Papillary Function and Repair After Reversible Ureteral Obstruction”, Am. Soc. Nephrol. Kidney
Spatially Resolved Transcriptomics Reveal Temporal Dynamics of Gene Expression Changes in a Model of Female AKI
Tuesday, November 16th, 2021
Eryn E. Dixon, Haojia Wu, Parker C. Wilson, Yoshiharu Muto, Benjamin D. Humphreys, “Spatially Resolved Transcriptomics Reveal Temporal Dynamics of Gene Expression Changes in a
Hypertensive Diabetic Kidney Disease Increases the Severity of Experimental AKI
Tuesday, November 16th, 2021
Anna Menshikh, Rachel Delgado, Maya Brewer, Min Yang, Chris R. Kennedy, Haichun Yang, Mark P. de Caestecker, “Hypertensive Diabetic Kidney Disease Increases the Severity of
Differential Role of Endothelial Prolyl-Hydroxylase 1, 2, 3 in AKI
Tuesday, November 16th, 2021
RatnakarTiwari, Si Young An, Pinelopi P. Kapitsinou, “Differential Role of Endothelial Prolyl-Hydroxylase 1, 2, 3 in AKI”, Am. Soc. Nephrol. Kidney Week Abstract Supplement: SA-OR20
Genetic Validation of Hdac8 as a Therapeutic Target for AKI
Tuesday, November 16th, 2021
Neil A. Hukriede, Rachel Delgado, Aneta J. Przepiorski, Michael D. McDaniels,1 Mark P. de Caestecker, “Genetic Validation of Hdac8 as a Therapeutic Target for AKI”,
mTOR Activity of Macula Densa (MD) Cells Is a Major Determinant of Glomerular Structure and Function
Tuesday, November 16th, 2021
Urvi Nikhil Shroff, Georgina Gyarmati, Audrey Izuhara, Janos Peti-Peterdi, “mTOR Activity of Macula Densa (MD) Cells Is a Major Determinant of Glomerular Structure and Function”,
Targeting High Mobility Group Box 1 with Inhibitors Attenuate Acute Kidney Injury in Postischemic Kidneys
Monday, June 21st, 2021
Zhibo Zhao, Julian Aurelio Marschner, Chenyu Li, Anders Hans-Joachim, “Targeting High Mobility Group Box 1 with Inhibitors Attenuate Acute Kidney Injury in Postischemic Kidneys”, ERA-EDTA
Asymtomatic Hyperuricemia Acta as Antioxidant During Acute Kidney Injury and Disease
Monday, June 21st, 2021
Qiuyue Ma, Viviane Gnemmi, Anders Hans-Joachim, Stefanie Steiger, “Asymtomatic Hyperuricemia Acta as Antioxidant During Acute Kidney Injury and Disease”, ERA-EDTA Meeting 2021, conference abstract MO328
Dual Blockade of Endothelin a Receptor (ETA) and Sodium-Glucose Cotransporter 2 (SGLT2) to Prevent Diabetic Kidney Disease Progression on a Type 2 Murine Model
Monday, June 21st, 2021
Ander Vergara Arana, Mireia Molina, Conxita Jacobs Cacha, Pamela Dominguez, Begona Benito, Irene Agraz Daniel Seron Micas, Marıa Jose´ Soler, “Dual Blockade of Endothelin a
Tubular Epithelial Cell Polyploidy is Essential to Survive AKI but it Contributes to CKD Progression
Monday, June 21st, 2021
Letizia De Chiara, Elena Lazzeri, Paola Romagnani, “Tubular Epithelial Cell Polyploidy is Essential to Survive AKI but it Contributes to CKD Progression”, ERA-EDTA Meeting 2021,
Hyperuricemia has Vasoactive Effects in Cholesterol Crystal-Induced Acute Kidney Injury
Monday, June 21st, 2021
Luying Yang, Elmina Mammadova-Bach, Attila Braun, Thomas Gudermann, Hans-Joachim Anders, Stefanie Steiger, “Hyperuricemia has Vasoactive Effects in Cholesterol Crystal-Induced Acute Kidney Injury”, ERA-EDTA Meeting 2021,
Sequential Afferent-Targeted and Total Renal Denervation and Impact on Regulation of Arterial Pressure, Glomerular Filtration, and Sodium Handling in Sprague Dawley Male Rats
Tuesday, May 25th, 2021
Irin Parvin, Madeline Gauthier, Melissa Dennis, Christopher Banek, “Sequential Afferent-Targeted and Total Renal Denervation and Impact on Regulation of Arterial Pressure, Glomerular Filtration, and Sodium
Cannabinoid Administration Does Not Affect Mean Arterial Pressure or Glomerular Filtration Rate in DOCA-Salt Hypertensive Rats
Tuesday, May 25th, 2021
Madeline Gauthier, Melissa Rafet Dennis, Irin Parvin, Kyle Schwartz, Christopher Banek, “Cannabinoid Administration Does Not Affect Mean Arterial Pressure or Glomerular Filtration Rate in DOCA-Salt
Genetic Deletion of AT1a Receptors Selectively in The Proximal Tubules of The Kidney Attenuates Angiotensin II-induced Hypertensive and Glomerular Filtration Responses in Aging PT-Agtr1a-/- Mice
Tuesday, May 25th, 2021
Xiao Li, Rumana Hassan, Jia Zhuo, “Genetic Deletion of AT1a Receptors Selectively in The Proximal Tubules of The Kidney Attenuates Angiotensin II-induced Hypertensive and Glomerular
Reduction in Proximal Tubular Secretion Precedes Reduction in Glomerular Filtration Rate in the Adenine-Induced CKD Model
Friday, October 30th, 2020
Eleni Kougioumtzidou, Tasso Miliotis, Anna Granqvist, Magnus Soderberg, “Reduction in Proximal Tubular Secretion Precedes Reduction in Glomerular Filtration Rate in the Adenine-Induced CKD Model,” Am.
Differential Role of NAD+ Deficiency in Acute and Chronic Kidney Disease
Friday, October 30th, 2020
Anna Faivre, Elena Katsyuba, Thomas Verissimo, Carolyn Heckenmeyer, David Legouis, Sophie M. De Seigneux, “Differential Role of NAD+ Deficiency in Acute and Chronic Kidney Disease,”
Tonic Inhibition of Sodium Reabsorption by Na+/K+-ATPase in the Renal Proximal Tubule
Friday, October 30th, 2020
Shreya T. Mukherji, Luca Brambilla, Isabella Mayes, Laura C. Kutz, Jeff P. Mcdermott, Steven T. Haller, Michael F. Romero, Jiang Liu, Joseph I. Shapiro, Gustavo
Pathobiology of Cyst Progression in Nbce1A and Pkd1 (RC/RC) Mouse Models
Friday, October 30th, 2020
Deema A. Anaam, Heather L. Holmes, Adriana Gregory, Ka Thao, Alison Stiller, Peter C. Harris,Timothy L. Kline, Michael F. Romero, “Pathobiology of Cyst Progression in
Proximal Tubule-Specific DPP4 Deletion Slows Kidney Disease Progression in Obese Mice
Friday, October 30th, 2020
Ravi Nistala, Jing Ren, Jianzhong An, Tammy L. Strawn, Suryanshi Rawat, Priyanka Patel, Adam Whaley-Connell, “Proximal Tubule-Specific DPP4 Deletion Slows Kidney Disease Progression in Obese
Platelets vs. Neutrophils as Therapeutic Targets in Cholesterol Embolism-Related Arterial Occlusion, Kidney Infarction, and AKI
Friday, October 30th, 2020
Chongxu Shi, Hans J. Anders, “Platelets vs. Neutrophils as Therapeutic Targets in Cholesterol Embolism-Related Arterial Occlusion, Kidney Infarction, and AKI,” Am. Soc. Nephrol. Kidney Week
Fractional Excretion of NGAL Is Useful to Distinguish Prerenal Azotemia (PRA) from Acute Tubular Injury (ATI) in Mice
Thursday, October 29th, 2020
Nataliya Skrypnyk, Chris Altmann, Sarah Faubel, “Fractional Excretion of NGAL Is Useful to Distinguish Prerenal Azotemia (PRA) from Acute Tubular Injury (ATI) in Mice,” Am.
Sex as a Biological Variable in Cardiac Outcomes after AKI in Mice
Thursday, October 29th, 2020
Sarah Faubel, “Sex as a Biological Variable in Cardiac Outcomes after AKI in Mice,” Am. Soc. Nephrol. Kidney Week Abstract Supplement: PO0147 2020.
Proximal Tubule-specific Deletion Of Angiotensin Ii Type 1a Receptors In The Kidney Lowers Basal Blood Pressure And Attenuates Angiotensin Ii-induced Hypertension By Increasing Glomerular Filtration And The Pressure-natriuresis Response
Monday, September 21st, 2020
Xiao C Li, Ana P Leite, Liang Zhang, Jia L Zhuo, “Proximal Tubule-specific Deletion Of Angiotensin Ii Type 1a Receptors In The Kidney Lowers Basal
Effectiveness Of Investigational RNAi Therapeutics Targeting Liver Angiotensinogen In Experimental Chronic Kidney Disease
Monday, September 21st, 2020
Dominique M Bovee, Liwei Ren, Don Foster, A.H. J Danser, “Effectiveness Of Investigational RNAi Therapeutics Targeting Liver Angiotensinogen In Experimental Chronic Kidney Disease,” American Heart
Role Of Angiotensin In Determining Blood Flow Remaining Kidney Following Nephrectomy
Monday, September 21st, 2020
Satoshi Shimada, Allen W Cowley, “Role Of Angiotensin In Determining Blood Flow Remaining Kidney Following Nephrectomy,” American Heart Association Journals – Hypertension, September 9, 2020,
The Effects of Chronic Dapagliflozin Treatment on the Renal Microvasculature in a Rat Model of Type 2 Diabetes
Wednesday, June 10th, 2020
Connie Ow, Vijayakumar Sukumaran, Jennifer Ngo, Cheng Kun Du, Akihiro Fujiwara, Hirotsugu Tsuchimochi, Hiroshi Hosoda, Roger Evans, James Pearson, “The Effects of Chronic Dapagliflozin Treatment
RENINAAV Dose-Dependently Exacerbate Albumninuria and Glomerulosclerosis, and Reduce GFR in Female Uninephrectomized DB/DB Mice
Wednesday, June 10th, 2020
Mette Viberg Østergaard1, Rune Ida1, Annemarie Aarup Pedersen,Thomas Secher, Frederikke Emilie Sembach, Sebastian Tølbøl Thrane, Urmas Roostalu, Keld Fosgerau, Lisbeth N Fink, Niels Vrang, “Dose
Dose Escalating Toxicology Study of ELP-VEGF, a Novel Biologic for Renal Therapeutic Angiogenesis
Wednesday, June 10th, 2020
Gene Bidwell, Jamarius Waller, Jason Engel, Alejandro Chade, “Dose Escalating Toxicology Study of ELP-VEGF, a Novel Biologic for Renal Therapeutic Angiogenesis,” ERA-EDTA Meeting 2020, Nephrology
Early, but Not Late, Contralateral Nephrectomy Overcomes Progression to CKD After Unilateral Ischemic Injury
Wednesday, June 10th, 2020
Lies Moonen, Cristina Cuesta-Apausa, Francisco J. Lopez-Hernandez, Carlos Martinez Salgado, Patrick D’Haese, Benjamin Vervaet, “Early, but Not Late, Contralateral Nephrectomy Overcomes Progression to CKD After
Necroinflammation Versus Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism-Related Kidney Infarct
Wednesday, June 10th, 2020
Chongxu Shi, “Necroinflammation Versus Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism-Related Kidney Infarct,” ERA-EDTA Meeting 2020, Nephrology Dialysis Transplantation 35 (Supplement 3):P0513.
Phase-Specific IRF4 and IRF8 Regulation/Expression of Mononuclear Phagocytes During Ischemic Acute Kidney Injury/Disease
Wednesday, June 10th, 2020
Na Li, Stefanie Steiger, Chenyu Li, Zhihua Zheng, Hans-Joachim Anders, Julia Lichtnekert, “Phase-Specific IRF4 and IRF8 Regulation/Expression of Mononuclear Phagocytes During Ischemic Acute Kidney Injury/Disease,”
Tubular Epithelial Cell Polyploidzation is Required to Survive AKI but Promotes CKD Development
Wednesday, June 10th, 2020
Letizia De Chiara, Elena Lazzeri, Maria Lucia Angelotti, Carolina Conte, Anna Julie Peired, Giulia Antonelli, Maria Elena Melica, Benedetta Mazzinghi, Laura Lasagni, Paola Romagnani, “Tubular
Deficiency of the Anaphylatoxin Receptors C5aR2 and C3aR Aggravates Hypertensive Renal Injury
Tuesday, January 21st, 2020
Marlies Bode, Catherine Meyer-Schwesinger, Christian Kurts, Heimo Ehmke, Joerg Koehl, Ulrich O. Wenzel, “Deficiency of the Anaphylatoxin Receptors C5aR2 and C3aR Aggravates Hypertensive Renal Injury,”
Deficiency of the Atypical Chemokine Receptor 2 (ACKR2) Accelerates Progression of Nephrocalcinosis-Related CKD
Monday, January 20th, 2020
Alexander Blaut, Nuru Eltrich, Hans J. Anders, Shrikant R. Mulay, VolkerVielhauer, “Deficiency of the Atypical Chemokine Receptor 2 (ACKR2) Accelerates Progression of Nephrocalcinosis-Related CKD,” Am.
Dietary Salt Modifies the Blood Pressure Response to Renin-Angiotensin Inhibition in Experimental CKD
Saturday, January 18th, 2020
Dominique M. Bovee, Catherina A. Cuevas, Alexander H. Danser, Robert Zietse, Ewout J. Hoorn, “Dietary Salt Modifies the Blood Pressure Response to Renin-Angiotensin Inhibition in
Effect of Canagliflozin on Glomerular Hyperfiltration Evaluated by Transcutaneous GFR Monitor in Spontaneously Diabetic Torii Fatty Rats
Thursday, January 16th, 2020
Goh Kodama, Yosuke Nakayama, Sakuya Ito, Yunosuke Yokota, Kei Fukami, “Effect of Canagliflozin on Glomerular Hyperfiltration Evaluated by Transcutaneous GFR Monitor in Spontaneously Diabetic Torii
Effects of AMPK Deficiency and Sex-Differences in Kidney Parameters Post Uninephrectomy
Wednesday, January 15th, 2020
Nuria M. Pastor-Soler, Kenneth R. Hallows, Jessica Pham, Daniel Rivera, Biagio Saitta, “Effects of AMPK Deficiency and Sex-Differences in Kidney Parameters Post Uninephrectomy,” Am. Soc.
Elevated Podocyte DAAM2 Expression in Diabetic Nephropathy
Tuesday, January 14th, 2020
Chenyang Qi, Haichun Yang, Raymond C. Harris, Agnes B. Fogo, “Elevated Podocyte DAAM2 Expression in Diabetic Nephropathy,” Am. Soc. Nephrol. Kidney Week Abstract Supplement: FR-PO192
Empagliflozin as an Add-On to Linagliptin Ameliorates Renal Interstitial Fibrosis in Spontaneously Diabetic Torii Fatty Rats
Monday, January 13th, 2020
Goh Kodama, Yosuke Nakayama, Sakuya Ito, Yunosuke Yokota, Yusuke Kaida, Kei Fukami, “Empagliflozin as an Add-On to Linagliptin Ameliorates Renal Interstitial Fibrosis in Spontaneously Diabetic
Ferritin Light Chain Confers Protection Against Sepsis-Induced Inflammation and Organ Injury
Sunday, January 12th, 2020
Abolfazl Zarjou, Laurence M. Black, Kayla R. McCullough, Travis D. Hull, Stephanie K. Esman, Ravindra Boddu, Sooryanarayana Varambally, Darshan S. Chandrashekar, Wenguang Feng, Paolo Arosio,
Genetic or Pharmacologic Activation of Nrf2 Worsens Glomerular Injury and Proteinuria
Saturday, January 11th, 2020
Brittney M. Rush, Corry D. Bondi, Sean D. Stocker, Roderick J. Tan, “Genetic or Pharmacologic Activation of Nrf2 Worsens Glomerular Injury and Proteinuria,” Am. Soc.
Glomerular filtrate proteins in acute cardiorenal syndrome
Friday, January 10th, 2020
Rumie Wakasaki, Katsuyuki Matsushita, Kirsti Golgotiu, Sharon Anderson, Mahaba B. Eiwaz, Daniel J. Orton, Sang Jun Han, H. Thomas Lee, Richard D. Smith, Karin D.
Glycogen synthase kinases 3-α/β inhibition attenuates progression of diabetic kidney disease beyond treatment with metformin/Ramipril/empagliflozin
Thursday, January 9th, 2020
Lidia Anguiano Gómez Manga Motrapu Julian Marschner Hans-Joachim Anders, “NGlycogen synthase kinases 3-α/β inhibition attenuates progression of diabetic kidney disease beyond treatment with metformin/Ramipril/empagliflozin,” Nephrology
GSK3-α/β Inhibition Attenuates Progression of CKD in Lepr-/- Mice with Type 2 Diabetes (T2D) Beyond Standard-of-Care Therapy (SOC) with Metformin/Ramipril/Empagliflozin
Wednesday, January 8th, 2020
Motrapu Manga, Lidia Anguiano-Gomez, Maria Lucia Angelotti, Paola Romagnani, Hans J. Anders, “SK3-α/β Inhibition Attenuates Progression of CKD in Lepr-/- Mice with Type 2 Diabetes
Impact of Aging on Transition of AKI to CKD
Sunday, January 5th, 2020
Myung-Gyu Kim, Jihyun Yang, Sewon Oh, Sang-Kyung Jo, “Impact of Aging on Transition of AKI to CKD,” Am. Soc. Nephrol. Kidney Week Abstract Supplement: FR-PO089
Inhibition of Lymphangiogenesis Exacerbates Cisplatin Nephrotoxicity
Saturday, January 4th, 2020
Elisa Farrell, “Inhibition of Lymphangiogenesis Exacerbates Cisplatin Nephrotoxicity,” Am. Soc. Nephrol. Kidney Week Abstract Supplement: SA-PO1178 2019.
Integrin β6 Knockout Ameliorates Glomerular Sensitization to Podocyte-Specific Injury
Friday, January 3rd, 2020
Jiayi Wang, Xin Li, Taiji Matsusaka, Haichun Yang, Agnes B. Fogo, “Integrin β6 Knockout Ameliorates Glomerular Sensitization to Podocyte-Specific Injury,” Am. Soc. Nephrol. Kidney Week
Kidneys Progressing from AKI to CKD Gradually Lose Their Inherent Potential to Recover
Thursday, January 2nd, 2020
Lies Moonen, Cristina Cuesta, Francisco J. Lopez-hernandez, Carlos Martinez-salgado, Patrick C. D’Haese, Benjamin A. Vervaet, “Kidneys Progressing from AKI to CKD Gradually Lose Their Inherent
Long-Term Outcomes in Mouse Models of Ischemia-Reperfusion-Induced AKI
Monday, December 30th, 2019
Anna Menshikh, Lauren N. Scarfe, Haichun Yang, Mark P. de Caestecker, “Long-Term Outcomes in Mouse Models of Ischemia-Reperfusion-Induced AKI,” Am. Soc. Nephrol. Kidney Week Abstract
Metformin Improves Relevant Disease Parameters in the Hypomorphic Pkd1RC/RC ADPKD Mouse Model
Saturday, December 28th, 2019
Kenneth R. Hallows, Hui Li, Pei-Yin Ho, Daniel Rivera, Biagio Saitta, Nuria M. Pastor-Soler, “Metformin Improves Relevant Disease Parameters in the Hypomorphic Pkd1RC/RC ADPKD Mouse
Myeloid Ferritin Heavy Chain Protects Against Ferroptosis in Ischemic AKI
Thursday, December 26th, 2019
Laurence M. Black, Kayla R. Mccullough, Amie Traylor, Evan Boitet, Jeremie M. Lever, Stephanie Esman, Daryll R. Spangler, Abolfazl Zarjou, Alecia K. Gross, Subhashini Bolisetty,
A Novel and Reproducible Model of CKD-Induced Vascular Calcification in Mice
Wednesday, December 25th, 2019
FarahAbou Daya, Daryll R. Spangler, Laurence M. Black, AmieTraylor, Abolfazl Zarjou, “A Novel and Reproducible Model of CKD-Induced Vascular Calcification in Mice,” Am. Soc. Nephrol.
SMPDL3b Regulates Proteinuria in Experimental Alport Syndrome
Sunday, December 22nd, 2019
Alla Mitrofanova, Antonio M. Fontanella, Judith T. Molina David, Javier T. Varona Santos, Lorenza Macrina, George W. Burke, Sandra M. Merscher, Alessia Fornoni, “SMPDL3b Regulates
A Novel Targeting Strategy That Can Prevent Cholesterol Crystal Embolism-Induced AKI and Kidney Infarction
Sunday, December 22nd, 2019
Chongxu Shi, Tehyung Kim, Stefanie Steiger, Barbara M. Klinkhammer, Peter Boor, Hans J. Anders, “A Novel Targeting Strategy That Can Prevent Cholesterol Crystal Embolism-Induced AKI
Paraoxonase 1 Regulation of Renal Inflammation and Fibrosis in CKD
Saturday, December 21st, 2019
Fatimah K. Khalaf, Chrysan J. Mohammed, Prabhatchandra Dube, Iman Tassavvor, Andrew Kleinhenz, Apurva Lad, Amira F. Gohara, Deepak K. Malhotra, Steven T. Haller, David J.
Polyploidization Is Essential to Survive AKI but It Contributes to CKD Development
Wednesday, December 18th, 2019
Letizia De Chiara, Elena Lazzeri, Maria Lucia Angelotti, Carolina Conte, Paola Romagnani, “Polyploidization Is Essential to Survive AKI but It Contributes to CKD Development,” Am.
Rapid Progression of Glomerulosclerosis due to Concurrent Diabetes and Hypertension Correlates with Podocyte Damage Shown by Expansion Microscopy
Tuesday, December 17th, 2019
Yalcin Kuzay, Euan Clark, Sara Medina Balbuena, Benito Yard, John Mullins, Wilhelm Kriz, Hermann-Josef Gröne, Sigrid C. Hoffmann, “Rapid Progression of Glomerulosclerosis due to Concurrent
Renal Microvascular Autoregulation in an Ischemia-Reperfusion-Induced Model of Acute Kidney Injury
Monday, December 16th, 2019
Bailey McEachen, “Renal Microvascular Autoregulation in an Ischemia-Reperfusion-Induced Model of Acute Kidney Injury,” Am. Soc. Nephrol. Kidney Week Abstract Supplement: SA-PO1170 2019.
Renal Olfactory Receptor 1393 Contributes to the Development and Progression of Type 1 Diabetes
Saturday, December 14th, 2019
Alexis R. Schiazza, Elizabeth G. Considine, Blythe D. Shepard, “Renal Olfactory Receptor 1393 Contributes to the Development and Progression of Type 1 Diabetes,” Am. Soc.
The Role of Renal Uric Acid Crystal Granulomas on CKD Progression in Mice and Humans
Thursday, December 12th, 2019
Stefanie Steiger, Markus Sellmayr, Moritz R. Hernandez Petzsche, Qiuyue Ma, Hans J. Anders, “The Role of Renal Uric Acid Crystal Granulomas on CKD Progression in
The Solute Carrier SLC16A12 Is Critical for Creatine and Guanidinoacetate Handling in the Kidney
Monday, December 9th, 2019
Sofia N. Verouti, Delphine Lambert, Escher Geneviève, Bruno Vogt, Daniel G. Fuster, “The Solute Carrier SLC16A12 Is Critical for Creatine and Guanidinoacetate Handling in the
Validation of Transcutaneous Fluorescence for Monitoring Gut Permeability
Thursday, December 5th, 2019
Jonathan Street, Asada Leelahavanichkul, Peter S. Yuen, Robert A. Star, “Validation of Transcutaneous Fluorescence for Monitoring Gut Permeability,” Am. Soc. Nephrol. Kidney Week Abstract Supplement:
Whole-Kidney 3D Imaging and Transcriptome Assessment in the UNxdb/db Mouse Model of Diabetic Nephropathy
Wednesday, December 4th, 2019
Diabetic Nephropathy Frederikke E. Sembach, Brandon B. Boland, Lisbeth N. Fink, Urmas Roostalu, Jacob L. Skytte, Thomas Secher, Keld Fosgerau, Niels Vrang, Jacob Jelsing, Jacob
Adipose-Derived Regenerative Cells: Therapeutic Potential
Monday, December 2nd, 2019
Rashida Lathan, Ryan Ghita, Patrick B. Mark, Marc J. Clancy, Rhian Touyz, Marc Clancy and Patrick Mark Team, “Adipose-Derived Regenerative Cells: Therapeutic Potential,” Am. Soc.
AMPK Deficiency Worsens Albuminuria Post Uninephrectomy (UNX)
Friday, November 29th, 2019
Daniel Rivera, Roshan Rajani, Valeria Mancino, Parisa Rezapoor, Hamidreza Zohoorkari, Biagio Saitta, Pei-Yin Ho, Hui Li, Kenneth R. Hallows, Nuria M. Pastor-Soler, “AMPK Deficiency Worsens
Dapagliflozin Reduces Glomerular Hyperfiltration and Improves Urine Parameters in db/db Mice on High Protein Diet: A 4-week Model of Diabetic Nephropathy
Monday, November 25th, 2019
Francois Briand, Sisse A. Nørgaard, Noémie Burr, Clément Costard, Emmanuel Brousseau, Nourdine Faresse, Fredrik Wolfhagen Sand, Thierry Sulpice, “Dapagliflozin Reduces Glomerular Hyperfiltration and Improves Urine
The Distribution Profile of Anti-Sense Oligonucleotides Indicates That Proximal Tubular Targets Should Be Prioritized in Renal Disease
Saturday, November 23rd, 2019
Anna Granqvist, Lena William-Olsson, Barbro Basta, Charlotte Ericson, Pernilla Tonelius, Åsa Wåhlander, Thomas Bell, Patrik Andersson, Magnus Soderberg, Robert J. Unwin, Mark J. Anderton, Christine
Endogenous Pentraxin 3 Inhibits Nephrocalcinosis and Protects from Hyperoxaluria-Induced CKD
Tuesday, November 19th, 2019
Julian A. Marschner, Shrikant R. Mulay, Lidia Anguiano, Stefanie Steiger, Antonio Inforzato Hans J. Anders, “Endogenous Pentraxin 3 Inhibits Nephrocalcinosis and Protects from Hyperoxaluria-Induced CKD,”
Endogenous pentraxin 3 inhibits nephrocalcinosis and protects from hyperoxalluria-induced Chronic Kidney Disease
Monday, November 18th, 2019
Julian A. Marschner, Shrikant R. Mulay, Stefanie Steiger, Lidia Anguiano, Antonio Inforzato, Cecilia Garlanda, Mantovani Alberto, Hans-Joachim Anders, “Endogenous pentraxin 3 inhibits nephrocalcinosis and protects
Regulation and Role of NADPH Oxidase 4 in CKD
Monday, November 18th, 2019
Sophie M. De Seigneux, Renuga Devi Rajaram, Anna Faivre, Vasiliki Delitsikou, Vincent Jaquet, Maja Lindenmeyer, Clemens D. Cohen, “Regulation and Role of NADPH Oxidase 4
Extracellular DNA Drives Cholesterol Crystal Embolism-Related Tissue Injury
Saturday, November 16th, 2019
Chongxu Shi, Shrikant R. Mulay, Barbara M. Klinkhammer, Helen Liapis, Peter Boor, Hans J. Anders, “Extracellular DNA Drives Cholesterol Crystal Embolism-Related Tissue Injury,” Am. Soc.
Genetic Nrf2 Enhancement Increases Proteinuric Renal Injury
Friday, November 15th, 2019
Brittney M. Rush, Corry D. Bondi, Kacie Barry, Sean D. Stocker, Soma Jobbagy, Donna B. Stolz, Dionysios Chartoumpekis, Thomas W. Kensler, Roderick J. Tan, “Genetic
Glomerular Injury and Progressive Cardiac Dysfunction in the Obese ZSF1 Rat, a New Model of Diabetic Nephropathy and Heart Failure with Preserved Ejection Fraction
Thursday, November 14th, 2019
Elyse Di marco, Erik Michaëlsson, Charlotte Ericson, Margareta Behrendt, Maria Stromstedt, Magnus Soderberg, Johannes Wikstrom, Anna Granqvist, “Glomerular Injury and Progressive Cardiac Dysfunction in the
Ischemia Time Effects Long-Term Kidney Function in a Murine Model of Unilateral Ischemic AKI
Tuesday, November 12th, 2019
Danielle Soranno, Lara A. Kirkbride-Romeo, Sarah Faubel, “Ischemia Time Effects Long-Term Kidney Function in a Murine Model of Unilateral Ischemic AKI,” Am. Soc. Nephrol. Kidney
Long-Lasting RNAi Therapeutics Targeting Angiotensinogen Induces a Robust and Durable Antihypertensive Effect
Sunday, November 10th, 2019
Estrellita Uijl, Katrina M. Mirabito Colafella, Ewout J. Hoorn, Jae B. Kim, Donald J. Foster, Alexander H. Danser, “Long-Lasting RNAi Therapeutics Targeting Angiotensinogen Induces a
Long-Term Sequelae of AKI: A Year-Long Male and Female Murine Model
Saturday, November 9th, 2019
Danielle Soranno, Sarah Faubel, “Long-Term Sequelae of AKI: A Year-Long Male and Female Murine Model,” Am. Soc. Nephrol. Kidney Week Abstract Supplement: TH-OPO090 2018.
Macrophage polarization and granuloma formation in hyperuricemia-associated chronic kidney disease
Thursday, November 7th, 2019
Markus Sellmayr, Qiuyue Ma, Moritz R. Hernandez Petzsche, Vivianne Gnemmi, Hans-Joachim Anders, Stefanie Steiger, “Macrophage polarization and granuloma formation in hyperuricemia-associated chronic kidney disease,” Klinikum
Megalin Deletion Prevents Long-Term Loss of Glomerular Filtration Rate After Rhabdomyolysis
Wednesday, November 6th, 2019
Katsuyuki Matsushita, JamesA.McCormick, Kiyoshi Mori, Motoko Yanagita, Michael Hutchens, “Megalin Deletion Prevents Long-Term Loss of Glomerular Filtration Rate After Rhabdomyolysis,” Am. Soc. Nephrol. Kidney Week
Microangiography Reveals the Protective Role of Liraglutide on Renal Microvascular Impairment in Rats with Metabolic Syndrome
Monday, November 4th, 2019
Vijayakumar Sukumaran, Hirotsugu Tsuchimochi, Takashi Sonobe, Mikiyasu Shirai, James T. Pearson, “Microangiography Reveals the Protective Role of Liraglutide on Renal Microvascular Impairment in Rats with
A New Mouse Model for Septic AKI with Vasopressor Support
Saturday, November 2nd, 2019
Brianna C. Halasa, Jonathan Street, Peter S. Yuen, Robert A. Star, “A New Mouse Model for Septic AKI with Vasopressor Support,” Am. Soc. Nephrol. Kidney
Papillary renal cell carcinoma originates from a population of renal progenitor cells and is promoted by Acute Kidney Injury
Friday, November 1st, 2019
Anna J. Peired, Giulia Antonelli, Maria Lucia Angelotti, Alessandro Sisti, Marco Allinovi, Maria Rosaria Raspollini, Paola Romagnani, “Papillary renal cell carcinoma originates from a population
AKI to CKD Transition After Acute Cardiorenal Syndrome in the Mouse
Friday, November 1st, 2019
Katsuyuki Matsushita, Turgay Saritas, James A. McCormick, Michael Hutchens, “AKI to CKD Transition After Acute Cardiorenal Syndrome in the Mouse,” Am. Soc. Nephrol. Kidney Week
Tubular cell hypertrophy via endocycle and proliferation of tubular progenitors are central mechanisms of response after AKI
Tuesday, October 29th, 2019
Elena Lazzeri, Maria Lucia Angelotti, Anna Julie Peired, Carolina Conte, Laura Lasagni, Paola Romagnani, “Tubular cell hypertrophy via endocycle and proliferation of tubular progenitors are
Varying Nephrectomy Delay Time After Unilateral Ischemic Injury Allows Development of an Animal Model with a Controllable Degree of Renal Dysfunction
Friday, October 25th, 2019
Lies Moonen, Cristina Cuesta, Patrick C. D’Haese, Francisco J. Lopezhernandez, Carlos Martinez-salgado, Benjamin A. Vervaet, “Varying Nephrectomy Delay Time After Unilateral Ischemic Injury Allows Development
Endocycle-Mediated Hypertrophy and Progenitor Proliferation as Central Mechanisms of Response to AKI
Friday, October 18th, 2019
Elena Lazzeri, Maria Lucia Angelotti, Anna J. Peired, Carolina Conte, Laura Lasagni, Paola Romagnani, “Endocycle-Mediated Hypertrophy and Progenitor Proliferation as Central Mechanisms of Response to
Gli1+ Pericytes Are Required for AKI Recovery and Regulate Renal Function
Wednesday, October 16th, 2019
Flavia G. Machado, Eoghainín O. Hainmhire, Benjamin D. Humphreys, “Gli1+ Pericytes Are Required for AKI Recovery and Regulate Renal Function,” Am. Soc. Nephrol. Kidney Week
The Impact of Uninephrectomy on Subsequent AKI Outcomes
Monday, October 14th, 2019
Myunggyu Kim, Hiroshi Kojima, Jonathan Street, Erik H. Koritzinsky, Xuzhen Hu, Peter S. Yuen, Robert A. Star, “The Impact of Uninephrectomy on Subsequent AKI Outcomes,”
Liraglutide Treatment Improves Renal Vascular Function in Zucker Rats as Visualized by Microangiography
Thursday, October 10th, 2019
Vijayakumar Sukumaran, Takashi Sonobe, Hirotsugu Tsuchimochi, Eisuke Tatsumi, Mikiyasu Shirai, James T. Pearson, “Liraglutide Treatment Improves Renal Vascular Function in Zucker Rats as Visualized by
Renal Fibrosis and Tubular Transport Adaptation Caused by Cardiac Arrest and Cardiopulmonary Resuscitation (CA/CPR) in Mice
Sunday, October 6th, 2019
Michael Hutchens, Rumie Wakasaki, Ian P. Coe,Mohammed Z. Ferdaus, James A. McCormick, Sharon Anderson, “Renal Fibrosis and Tubular Transport Adaptation Caused by Cardiac Arrest and

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