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Dietary fructose and high salt in young male Sprague Dawley rats induces salt-sensitive changes in renal function in later life
Friday, September 23rd, 2022
Peter E. Levanovich, Ana M. Daugherty, Dragana Komnenov, Noreen F. Rossi, “Dietary fructose and high salt in young male Sprague Dawley rats induces salt-sensitive changes
Gasdermin D-deficient mice are hypersensitive to acute kidney injury
Thursday, September 22nd, 2022
Wulf Tonnus, Francesca Maremonti, Alexia Belavgeni, Markus Latk, Yoshihiro Kusunoki, Anne Brucker, Anne von Mässenhausen, Claudia Meyer, Sophie Locke, Florian Gembardt, Kristina Beer, Paul Hoppenz,
Blood pressure-independent renoprotective effects of small interference RNA targeting liver angiotensinogen in experimental diabetes
Thursday, September 22nd, 2022
Edwyn O. Cruz-López, Liwei Ren,Estrellita Uijl, Marian C. Clahsen-van Groningen, Richard van Veghel, Ingrid M. Garrelds, Oliver Domenig, Marko Poglitsch, Ivan Zlatev, Timothy Rooney, Anne
Transdermal Measurement of Glomerular Filtration Rate in Mechanically Ventilated Piglets
Thursday, September 15th, 2022
Mina S. Fanous, Jeremiah M. Afolabi, Olugbenga S. Michael, Olufunke O. Falayi, Samson A. Iwhiwhu, Adebowale Adebiyi, “Transdermal Measurement of Glomerular Filtration Rate in Mechanically
Intravital imaging of hemodynamic glomerular effects of enalapril or/and empagliflozin in STZ-diabetic mice
Thursday, September 15th, 2022
Hannah Kroeger, Friederike Kessel, Jan Sradnick, Vladimir Todorov, Florian Gembardt, Christian Hugo, “Intravital imaging of hemodynamic glomerular effects of enalapril or/and empagliflozin in STZ-diabetic mice”,
A Novel Animal Model to Study Delayed Resuscitation Following Traumatic Hemorrhage
Tuesday, August 30th, 2022
Lusha Xiang, Alfredo S. Calderon, Harold G. Klemcke, Carmen Hinojosa-Laborde, Sandra C. Becerra, and Kathy L. Ryan, “A Novel Animal Model to Study Delayed Resuscitation
Endoplasmic reticulum stress contributes to cisplatin-induced chronic kidney disease via the PERK–PKCδ pathway
Tuesday, August 2nd, 2022
Shaoqun Shu, Hui Wang, Jiefu Zhu, Ying Fu, Juan Cai, Anqun Chen, Chengyuan Tang & Zheng Dong, “Endoplasmic reticulum stress contributes to cisplatin-induced chronic kidney
Renal Deletion of LRRC8/VRAC Channels Induces Proximal Tubulopathy
Tuesday, July 5th, 2022
Karen I. L opez-Cayuqueo, Rosa Planells-Cases, Matthias Pietzke, Anna Oliveras, Stefan Kempa, Sebastian Bachmann, and Thomas J. Jentsch, “Renal Deletion of LRRC8/VRAC Channels Induces Proximal Tubulopathy,”
Influence of carnosine and carnosinase-1 on diabetes-induced afferent arteriole vasodilation: implications for glomerular hemodynamics
Monday, June 6th, 2022
Angelica Rodriguez-Niño, Diego O. Pastene*, Steffen A. Hettler, Jiedong Qiu, Thomas Albrecht, Srishti Vajpayee, Rossana Perciaccante, Norbert Gretz, Stephan J.L. Bakker, Bernhard K. Krämer, Benito
The Release of 24 h Infravesical Obstruction in Mice: Changes in Molecular, Morphological, and Functional Parameters for 14-Day Observation
Tuesday, May 31st, 2022
Yutao Lu, Scott R. Manson, Isabela Bastos Binotti Abreu de Araujo, Paul F. Austin, Jens C. Djurhuus, L. Henning Olsen and Rikke Nørregaard, “The Release
Inhibitor of MyoD family isoform a (I-mfa) regulates contractile function of glomerular mesangial cells and glomerular filtration rate
Wednesday, May 18th, 2022
Garland Siebert, Parisa Yazdizadeh Shotorbani, Yu Tao, Zheng Chen, Rong Ma, “Inhibitor of MyoD family isoform a (I-mfa) regulates contractile function of glomerular mesangial cells
Paraoxonase-1 Regulation of Renal Inflammation and Fibrosis in Chronic Kidney Disease
Monday, May 9th, 2022
Fatimah K. Khalaf, Chrysan J. Mohammed, Prabhatchandra Dube, Jacob A. Connolly, Apurva Lad, Usman M. Ashraf, Joshua D. Breidenbach, Robin C. Su, Andrew L. Kleinhenz,
Cardiometabolic effects of DOCA-salt in male C57BL/6J mice are variably dependent on sodium and nonsodium components of diet
Thursday, April 28th, 2022
Chetan N. Patil, McKenzie L. Ritter, Kelsey K. Wackman, Vanessa Oliveira, Kirthikaa Balapattabi, Connie C. Grobe, Daniel T. Brozoski, John J. Reho, Pablo Nakagawa, Gary
Endothelial Cullin3 Mutation Impairs Nitric Oxide-Mediated Vasodilation and Promotes Salt-Induced Hypertension
Tuesday, April 12th, 2022
Jing Wu, Shi Fang, Ko-Ting Lu, Gaurav Kumar, John J Reho, Daniel T Brozoski, Adokole J Otanwa, Chunyan Hu, Kelsey K Wackman, Larry N Agbor,
A Translational Rat Model to Assess Glomerular Function Changes with Vancomycin
Monday, April 4th, 2022
Gwendolyn M. Paisab, Jack Chang, Jiajun Liu, Marc H. Scheetz, “A Translational Rat Model to Assess Glomerular Function Changes with Vancomycin”, International Journal of Antimicrobial
Decreased Renal Gluconeogenesis Is a Hallmark of Chronic Kidney Disease
Tuesday, March 29th, 2022
Thomas Verissimo, Anna Faivre, Anna Rinaldi, Maja Lindenmeyer, Vasiliki Delitsikou, Christelle Veyrat-Durebex, Carolyn Heckenmeyer, Marylise Fernandez, Lena Berchtold, Delal Dalga, Clemens Cohen, Maarten Naesens, Sven-Erik
Validation of HDAC8 Inhibitors as Drug Discovery Starting Points to Treat Acute Kidney Injury
Tuesday, March 29th, 2022
Keith Long, Zoe Vaughn, Michael David McDaniels, Sipak Joyasawal, Aneta Przepiorski, Emily Parasky, Veronika Sander, David Close, Paul A.Johnston, Alan J. Davidson, Mark de Caestecker,
Murine models of renal ischemia reperfusion injury: An opportunity for refinement using noninvasive monitoring methods
Tuesday, March 29th, 2022
Rachel Harwood, Joshua Bridge, Lorenzo Ressel, Lauren Scarfe, Jack Sharkey, Gabriela Czanner, Philip A Kalra, Aghogho Odudu, Simon Kenny, Bettina Wilm, Patricia Murray, “Murine models of renal ischemia reperfusion injury: An opportunity for refinement using noninvasive
Sirtuin 7 Deficiency Reduces Inflammation and Tubular Damage Induced by an Episode of Acute Kidney Injury
Friday, March 11th, 2022
Andrea Sánchez-Navarro, Miguel Ángel Martínez-Rojas, Adrián Albarrán-Godinez, Rosalba Pérez-Villalva, Johan Auwerx, Abigail de la Cruz, Lilia G. Noriega, Florencia Rosetti, and Norma A. Bobadilla, “Sirtuin
Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease
Friday, March 11th, 2022
Mette V. Østergaard, Thomas Secher, Michael Christensen, Casper Gravesen Salinas, Urmas Roostalu, Jacob Lercke Skytte, Ida Rune, Henrik H. Hansen, Jacob Jelsing, Niels Vrang, and
Divergent roles of angiotensin II upon the immediate and sustained increases of renal blood flow following unilateral nephrectomy
Friday, March 11th, 2022
Satoshi Shimada, Chun Yang, Theresa Kurth, and Allen W. Cowley Jr., “Divergent roles of angiotensin II upon the immediate and sustained increases of renal blood
p53 in Proximal Tubules Mediates Chronic Kidney Problems after Cisplatin Treatment
Thursday, February 24th, 2022
Shuangshuang Fu, Xiaoru Hu, Zhengwei Ma, Qingqing Wei, Xiaohong Xiang, Siyao Li, Lu Wen, Yumei Liang and Zheng Dong, “p53 in Proximal Tubules Mediates Chronic
Asymptomatic Hyperuricemia Promotes Recovery from Ischemic Organ Injury by Modulating the Phenotype of Macrophages
Wednesday, February 16th, 2022
Viviane Gnemmi, Qiubo Li, Qiuyue Ma, Letizia De Chiara, Giulia Carangelo, Chenyu Li, Mireia Molina-Van den Bosch, Paola Romagnani, Hans-Joachim Anders and Stefanie Steiger,”Asymptomatic Hyperuricemia
Tourniquet-induced lower limb ischemia/reperfusion reduces mitochondrial function by decreasing mitochondrial biogenesis in acute kidney injury in mice
Saturday, February 12th, 2022
Balamurugan Packialakshmi, Ian J. Stewart, David M. Burmeister, Yuanyi Feng, Dennis P. McDaniel, Kevin K. Chung, Xiaoming Zhou, “Tourniquet-induced lower limb ischemia/reperfusion reduces mitochondrial function
Salt loading with unilateral nephrectomy accelerates decline in glomerular filtration rate in the hypertensive, obese, type 2 diabetic SDT fatty rat model of diabetic kidney disease
Thursday, February 3rd, 2022
Yuichi Shinozaki, Yuko Katayama, Fuminari Yamaguchi, Tomohisa Suzuki, Kana Watanabe, Kinuko Uno, Takahiro Tsutsui, Miki Sugimoto, Masami Shinohara, Katsuhiro Miyajima, Takeshi Ohta, “Salt loading with
Metabolomic Study on Iohexol-Induced Nephrotoxicity in Rats Based on NMR and LC–MS Analyses
Thursday, February 3rd, 2022
Liming Wang, Shuo Huang, Tongtong Zhu, Xiaoyan Ge, Chenxi Pei, Ge Hong, and Lifeng Han, “Metabolomic Study on Iohexol-Induced Nephrotoxicity in Rats Based on NMR
Nephron mass determines the excretion rate of urinary extracellular vesicles
Tuesday, January 25th, 2022
Charles J. Blijdorp MD, Thomas A. Hartjes MSc, Kuang-YuWei MD, Martijn H. van Heugten MD, Dominique M. Bovee MD, Ricardo P.J. Budde MD, PhD, Jacqueline van
Mechanochemical prepared ibuprofen-Polygonatum sibiricum polysaccharide drug delivery system for enhanced bioactivity with reduced renal injury induced by NSAIDs
Tuesday, January 25th, 2022
Wenhao Xu, Jinli Yang, Xiangyang Gu, Wenjing Su, Faxiang Pu, Zhangfu Xie, Kongliang Jin, Weike Su & Lichan Mao,”Mechanochemical prepared ibuprofen-Polygonatum sibiricum polysaccharide drug delivery
Treatment With Lisinopril Prevents the Early Progression of Glomerular Injury in Obese Dahl Salt-Sensitive Rats Independent of Lowering Arterial Pressure
Tuesday, December 28th, 2021
Andrea K. Brown, Alyssa Nichols, Chantell A. Coley, Ubong S. Ekperikpe, Kasi C. McPherson, Corbin A. Shields, Bibek Poudel, Denise C. Cornelius, Jan M. Williams,
Empagliflozin Reduces Renal Hyperfiltration in Response to Uninephrectomy, but Is Not Nephroprotective in UNx/DOCA/Salt Mouse Models
Tuesday, December 28th, 2021
Philipp Tauber, Frederick Sinha, Raffaela S. Berger, Wolfram Gronwald, Katja Dettmer, Michaela Kuhn, Maximilian Trum, Lars S. Maier, Stefan Wagner, Frank Schwed, “Empagliflozin Reduces Renal
Dichotomous responses to chronic fetal hypoxia lead to a predetermined aging phenotype
Tuesday, December 28th, 2021
Stefan Rudloff, Andrea Bileck, Lukas Janker, Nicola Wanner, Nastassia Liaukouskaya, Carsten Lundby, Tobias B. Huber, Christopher Gerner, Uyen Huynh-Do, “Dichotomous responses to chronic fetal hypoxia
Loss of renal olfactory receptor 1393 leads to improved glucose homeostasis in a type 1 diabetic mouse model
Thursday, December 9th, 2021
Alexis R. Schiazza, Elizabeth G. Considine, Madison Betcher, Blythe D. Shepard, ” Loss of renal olfactory receptor 1393 leads to improved glucose homeostasis in a
Activation of the Hypoxia-Inducible Factor Pathway Inhibits Epithelial Sodium Channel–Mediated Sodium Transport in Collecting Duct Principal Cells
Wednesday, December 8th, 2021
Eva Dizin, Valérie Olivier, Isabelle Roth, Ali Sassi, Grégoire Arnoux, Suresh Ramakrishnan, Sandrine Morel, Brenda R. Kwak, Johannes Loffing, Edith Hummler, Roland H. Wenger, Ian
A new view of macula densa cell protein synthesis
Wednesday, December 8th, 2021
Urvi Nikhil Shroff, Georgina Gyarmati, Audrey Izuhara, Sachin Deepak, and János Peti-Peterdi, “A new view of macula densa cell protein synthesis”, American Journal of Physiology,
Kidney vascular congestion exacerbates acute kidney injury in mice.
Wednesday, December 8th, 2021
Takashi Kitani, Kengo Kidokoro, Tomohiro Nakata, Yuhei Kirita, Itaru Nakamura, Kunihiro Nakai, Aya Yagi-Tomita, Tomoharu Ida, Noriko Uehara-Watanabe, Kisho Ikeda, Noriyuki Yamashita, Benjamin D. Humphreys,
Novel Keap1-Nrf2 Protein-protein interaction inhibitor UBE-1099 Ameliorates Progressive Phenotype in Alport Syndrome mouse model
Wednesday, December 8th, 2021
Shota Kaseda, Yuya Sannomiya, Jun Horizono, Jun Kuwazuru, Mary Ann Suico, Sayaka Ogi, Ryoko Sasaki, Hidetoshi Sunamoto, Hirohiko Fukiya, Hayato Nishiyama, Misato Kamura, Saki Niinou,
Spatially Resolved Transcriptomic Analysis of Acute Kidney Injury in a Female Murine Model
Wednesday, December 8th, 2021
ryn Dixon, Haojia Wu, Yoshiharu Muto, Parker Wilson and Benjamin Humphreys, “Spatially Resolved Transcriptomic Analysis of Acute Kidney Injury in a Female Murine Model”, JASN
Relaxin attenuates organ fibrosis via an angiotensin-type 2 receptor mechanism in aged hypertensive female rats
Tuesday, November 30th, 2021
Giannie Barsha, Sarah Walton, Edmund Kwok, Katrina Mirabito Colafella, Anita Pinar, Lucinda Hilliard Krause, Tracey Gaspari, Robert Widdop, Chrishan Samuel and Kate Denton, “Relaxin attenuates
Metformin Improves Relevant Disease Parameters in an Autosomal Dominant Polycystic Kidney Disease Mouse Model
Tuesday, November 30th, 2021
Núria M. Pastor-Soler, Hui Li, Jessica Pham, Daniel Rivera, Pei-Yin Ho, Valeria Mancino, Biagio Saitta and Kenneth R. Hallows, “Metformin Improves Relevant Disease Parameters in
Expanded renal lymphatics improve recovery following kidney injury
Tuesday, November 30th, 2021
Gaurav Baranwal, Heidi A. Creed, Laurence M. Black, Alexa Auger, Alexander M. Quach, Rahul Vegiraju, Han E. Eckenrode, Anupam Agarwal, Joseph M. Rutkowski, “Expanded renal
Angiotensin II type 1 receptor agonistic autoantibody blockade improves postpartum hypertension and cardiac mitochondrial function in rat model of preeclampsia
Tuesday, November 16th, 2021
George W. Booz, Daniel Kennedy, Michael Bowling, Taprieka Robinson, Daniel Azubuike, Brandon Fisher, Karen Brooks, Pooja Chinthakuntla, Ngoc H. Hoang, Jonathan P. Hosler and Mark
Noninvasive assessment of radiation-induced renal injury in mice
Friday, November 5th, 2021
Anis Ahmad, Junwei Shi, Saba Ansari, Jumana Afaghani, Judith Molina, Alan Pollack, Sandra Merscher, Youssef H Zeidan, Alessia Fornoni, Brian Marples, “Noninvasive assessment of radiation-induced
Glutathione S-Transferase and Clusterin, New Players in the Ischemic Preconditioning Renal Protection in a Murine Model of Ischemia and Reperfusion
Thursday, November 4th, 2021
Consuelo Pasten, Yeimi Herrera-Luna, Mauricio Lozano, Jocelyn Rocco, Cristobal Alvarado, Jéssica Liberona, Luis Michea, Carlos E Irarrázabal, “Glutathione S-Transferase and Clusterin, New Players in the
Loss of Functional SCO2 Attenuates Oxidative Stress in Diabetic Kidney Disease
Saturday, October 30th, 2021
Nehaben A. Gujarati, Alexandra R. Leonardo, Jessica M. Vasquez, Yiqing Guo, Bismark O. Frimpong, Elbek Fozilov, Monica P. Revelo, Ilse S. Daehn, John C. He,
The non-steroidal mineralocorticoid receptor antagonist finerenone improves left ventricular function in preclinical chronic kidney disease
Monday, October 25th, 2021
Y Stephan, I Lima-Posada, M Souille, B Bonnard, R Palacios, L Nicol, P Kolkhof, F Jaisser, P Mulder, “The non-steroidal mineralocorticoid receptor antagonist finerenone improves
VEGFR3 tyrosine kinase inhibition aggravates cisplatin nephrotoxicity
Thursday, October 21st, 2021
Laurence M Black, Elisa R Farrell, Daria Barwinska, Gunars Osis, Anna A Zmijewska, Amie M. Traylor, Stephanie K Esman, Subhashini Bolisetty, Grace Whipple, Malgorzata M.
Therapeutic silencing of SMOC2 prevents kidney function loss in mouse model of chronic kidney disease
Tuesday, October 19th, 2021
Cuiyan Xin, Jiahui Lei, Qian Wang, Yixia Yin, Xiaoqian Yang, Jose Alberto Moran Guerrero, Venkata Sabbisetti, Xiaoming Sun, Vishal S. Vaidya, Joseph V. Bonventre, “Therapeutic
Measurement of glomerular filtration rate reveals that subcapsular injection of shear-thinning hyaluronic acid hydrogels does not impair kidney function in mice
Friday, October 1st, 2021
Danielle E. Soranno, Lara Kirkbride-Romeo, Daniel Han, Christopher Altmann, Christopher B. Rodell, “Measurement of glomerular filtration rate reveals that subcapsular injection of shear-thinning hyaluronic acid
High salt diet-induced proximal tubular phenotypic changes and sodium-glucose cotransporter-2 expression are coordinated by cold shock Y-box binding protein-1
Friday, September 24th, 2021
Anja Bernhardt, Saskia Häberer, JingJing Xu, Hannah Damerau, Johannes Steffen, Charlotte Reichardt, Katharina Wolters, Hannes Steffen, Berend Isermann, Katrin Borucki, Nadine Artelt, Nicole Endlich, Renata
Cilastatin Ameliorates Rhabdomyolysis-Induced Acute Kidney Injury in Mice
Monday, August 9th, 2021
Katsuyuki Matsushita, Kiyoshi Mori, Turgay Saritas, Mahaba Eiwaz, Yoshio Funahashi, Megan Nickerson, Jessica Hebert, Adam Munhall, James McCormick, Motoko Yanagita and Michael Hutchens,”Cilastatin Ameliorates Rhabdomyolysis-Induced
The PI3Kδ inhibitor parsaclisib ameliorates pathology and reduces autoantibody formation in preclinical models of systemic lupus erythematosus and Sjӧgren’s syndrome
Thursday, July 29th, 2021
Monika D.Scuron, Brittany L.Fay, Andrew J.Connell, JulianOliver, Paul A.Smith, “The PI3Kδ inhibitor parsaclisib ameliorates pathology and reduces autoantibody formation in preclinical models of systemic lupus
Therapeutic effects of lisinopril and empagliflozin in a mouse model of hypertension-accelerated diabetic kidney disease
Thursday, July 29th, 2021
Mette V. Østergaard, Thomas Secher, Michael Christensen, Casper Gravesen Salinas, Urmas Roostalu, Jacob Lercke Skytte, Ida Rune, Henrik H. Hansen, Jacob Jelsing, Niels Vrang, and
The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)
Thursday, June 24th, 2021
Aowen Zhuang1, Felicia Y. T. Yap, Danielle J. Borg, Domenica McCarthy, Amelia Fotheringham, Sherman Leung, Sally A. Penfold, Karly C. Sourris, Melinda T. Coughlan, Benjamin
Pharmacological HIF-PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation
Thursday, June 3rd, 2021
Mikhail Burmakin, Angelica Fasching, Hanako Kobayashi, Andrés A Urrutia, Anastasios Damdimopoulos, Fredrik Palm, Volker H Haase, “Pharmacological HIF-PHD inhibition reduces renovascular resistance and increases glomerular
Renal tolerance to delayed volume resuscitation following traumatic shock
Thursday, May 20th, 2021
Lusha Xiang, Alfredo Calderon, Brian Connor, Luciana Torres, Carmen Hinojosa-Laborde, Kathy Ryan, “Renal tolerance to delayed volume resuscitation following traumatic shock”, The FASEB Journal, Physiology,
Activation of hypoxia-sensing pathways promotes renal ischemic preconditioning following myocardial infarction
Sunday, May 2nd, 2021
Andrew S. Terker, Kensuke Sasaki, Juan Pablo Arroyo, Aolei Niu, Suwan Wang, Xiaofeng Fan, Yahua Zhang, Sochinweichi Nwosisi, Ming-Zhi Zhang, and Raymond C. Harris, “Activation
Loss of Soluble (Pro)renin Receptor Attenuates Angiotensin-II Induced Hypertension and Renal Injury
Tuesday, April 27th, 2021
Nirupama Ramkumar, Deborah Stuart, Caitlin S Peterson, Chunyan Hu, William Wheatley, Jae-Min Cho, J David Symons, and Donald E Kohan, “Loss of Soluble (Pro)renin Receptor
Acute Kidney Injury Results in Long-Term Diastolic Dysfunction That Is Prevented by Histone Deacetylase Inhibition
Thursday, April 1st, 2021
Danielle E. Soranno, Lara Kirkbride-Romeo, Sara A. Wennersten, Kathy Ding, Maria A. Cavasin, Peter Baker, Christopher Altmann, Rushita A. Bagchi, Korey R. Haefner, Christian Steinkühler,
A dose-escalating toxicology study of the candidate biologic ELP-VEGF
Wednesday, March 24th, 2021
Jamarius P Waller, Stephen P Burke, Jason Engel, Alejandro R Chade, Gene L Bidwell 3rd, “A dose-escalating toxicology study of the candidate biologic ELP-VEGF”, Scientifc
Glomerular hyperfiltration with hyperglycemia in the spontaneously diabetic Torii (SDT) fatty rat, an obese type 2 diabetic model
Wednesday, March 24th, 2021
R Sano, Y Ishii, M Yamanaka, Y Yasui, Y Kemmochi, F Kuroki, M Sugimoto, S Fukuda, T Sasase, K Miyajima, D Nakae, T Ohta, “Glomerular
Osthol Ameliorates Kidney Damage and Metabolic Syndrome Induced by a High-Fat/High-Sugar Diet
Wednesday, March 10th, 2021
Fernando E. García-Arroyo, Guillermo Gonzaga-Sánchez, Edilia Tapia, Itzel Muñoz-Jiménez, Lino Manterola-Romero, Horacio Osorio-Alonso, Abraham S. Arellano-Buendía, José Pedraza-Chaverri, Carlos A. Roncal-Jiménez, Miguel A. Lanaspa, Richard
Proximal Tubule-Specific Deletion of Angiotensin II Type 1a Receptors in the Kidney Attenuates Circulating and Intratubular Angiotensin II-Induced Hypertension in PT- Agtr1a-/- Mice
Tuesday, March 9th, 2021
Xiao Chun Li, Ana Paula Oliveira Leite, Xiaowen Zheng, Chunling Zhao, Xu Chen, Liang Zhang, Xinchun Zhou, Isabelle Rubera, Michel Tauc, Jia Long Zhuo, “Proximal
Dietary Salt Modifies the Blood Pressure Response to Renin-Angiotensin Inhibition in Experimental Chronic Kidney Disease
Thursday, February 25th, 2021
Dominique M Bovee, Estrellita Uijl, David Severs, Eloisa Rubio-Beltrán, Richard van Veghel, Antoinette Maassen van den Brink, Jaap A Joles, Robert Zietse, Catherina Adelie Cuevas,
A multicenter blinded preclinical randomized controlled trial on Jak1/2 inhibition in MRL/MpJ-Faslpr mice with proliferative lupus nephritis predicts low effect size
Thursday, February 25th, 2021
Yutian Lei, Bettina Sehnert PhD, Reinhard E.Voll MD, Conxita Jacobs-Cach PhD, Maria Jose Soler MD, PhD, Maria D. Sanchez-Niño PhD, Alberto Ortiz MD,PhD, Roman D.
Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease
Thursday, February 25th, 2021
Markus Sellmayr, Moritz Roman Hernandez Petzsche, Qiuyue Ma, Nils Krüger, Helen Liapis, Andreas Brink, Barbara Lenz, Maria Lucia Angelotti, Viviane Gnemmi, Christoph Kuppe, Hyojin Kim,
Glomerular hyperfiltration with hyperglycemia in the Spontaneously Diabetic Torii (SDT) fatty rat, an obese type 2 diabetic model
Monday, January 25th, 2021
Ryuhei Sano, Yukihito Ishi, Masao Yamanaka1, Yuzo Yasui, Yusuke Kemmochi, Fuko Kuroki, Miki Sugimoto, Sumiaki Fukuda, Tomohiko Sasase, Katsuhiro Miyajima, Dai Nakae, Takeshi Ohta, “Glomerular
Non-invasive Assessment of Radiation-Induced Renal Injury in Mice
Monday, January 25th, 2021
Anis Ahmad, Junwei Shi, Saba Ansari, Jumana Afaghani, Judith Molina, Alan Pollack, Sandra Merscher, Youssef H. Zeidan, Alessia Fornoni, & Brian Marples, “Non-invasive Assessment of
Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress
Monday, January 25th, 2021
Stefan Rudloff, Mathilde Janot, Stephane Rodriguez1, Kevin Dessalle, Willi Jahnen-Dechent, & Uyen Huynh-Do, “Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress,”
Endothelial SOCS3 Maintains Homeostasis and Promotes Survival in Endotoxemic Mice
Wednesday, January 13th, 2021
Nina Martino, Ramon Bossardi Ramos, Shuhan Lu, Kara Leyden, Lindsay Tomaszek, Ariel Jaitovich, Peter A. Vincent, Alejandro P. Adam, “Endothelial SOCS3 Maintains Homeostasis and Promotes
No Evidence for Brain Renin-Angiotensin System Activation During DOCA-Salt Hypertension
Wednesday, January 13th, 2021
Estrellita Uij, Liwei Ren, Katrina M. Mirabito Colafella, Richard van Veghel1, Ingrid M. Garrelds, Oliver Domenig, Marko Poglitsch, Ivan Zlatev, Jae B. Kim, Stephen Huang,
Intrarenal Renin Angiotensin System Imbalance During Postnatal Life Is Associated With Increased Microvascular Density in the Mature Kidney
Monday, November 23rd, 2020
Carolina Dalmasso, Alejandro R. Chade, Mariela Mendez, Jorge F. Giani, Gregory J. Bix, Kuey C. Chen and Analia S. Loria, “Intrarenal Renin Angiotensin System Imbalance
Acute kidney injury during pregnancy leads to increased sFlt-1 and sEng and decreased renal T regulatory cells in pregnant rats with HELLP syndrome
Tuesday, September 29th, 2020
Jamie Szczepanski, Shauna-Kay Spencer, Ashley Griffin, Teylor Bowles, Jan Michael Williams, Patrick B. Kyle, John Polk Dumas, Sarah Araji and Kedra Wallace, “Acute kidney injury
Regular exercise and branched-chain amino acids prevent ischemic acute kidney injury-related muscle wasting in mice
Monday, August 31st, 2020
Soichiro Nagata, Akihiko Kato, Shinsuke Isobe, Tomoyuki Fujikura, Naro Ohashi, Hiroaki Miyajima, Hideo Yasuda, “Regular exercise and branched-chain amino acids prevent ischemic acute kidney injury-related
Genetic or Pharmacologic Nrf2 Activation Increases Proteinuria in Chronic Kidney Disease in Mice
Monday, August 24th, 2020
Brittney M. Rush, Corry D. Bondi, Sean D. Stocker, Kacie M. Barry,Sarah A. Small,Jason Ong, Soma Jobbagy, Donna B. Stolz, Sheldon I. Bastacky, Dionysios, V.
Drug Testing for Residual Progression of Diabetic Kidney Disease in Mice Beyond Therapy with Metformin, Ramipril, and Empagliflozin
Monday, July 13th, 2020
Manga Motrapu, Monika Katarzyna Swiderska, Irene Mesas, Julian Aurelio Marschner, Yutian Lei, Laura Martinez Valenzuela, Jia Fu, Kyung Lee, Maria Lucia Angelotti, Giulia Antonelli, Paola
Cardiac, renal and uterine hemodynamics changes throughout pregnancy in rats with a prolonged high fat diet from an early age
Monday, July 13th, 2020
Lidia Oltra, Virginia Reverte, Antonio Tapia, Juan M. Moreno, Francisco J. Salazar, Maria T. Llinas, “Cardiac, renal and uterine hemodynamics changes throughout pregnancy in rats
Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and endothelial dysfunction with signs of cardiomyopathy of obesity
Wednesday, June 24th, 2020
Bochra Tourki, Vasundhara Kain, Saame Raza Shaikh, Xavier Leroy, Charles N. Serhan, Ganesh V. Halade, “Deficit of resolution receptor magnifies inflammatory leukocyte directed cardiorenal and
Discovery of diarylamides as novel orally active diuretics targeting urea transporters
Wednesday, June 24th, 2020
Shun Zhang, Yan Zhao, Shuyuan Wang, Min Li, Yue Xu, Jianhua Ran, Xiaoqiang Geng, Jinzhao He, Jia Meng, Guangying Shao, Hong Zhou, Zemei Ge, Guangping
NLRP3 inflammasome inhibition attenuates sepsis-induced platelet activation and prevents multi-organ injury in cecal-ligation puncture
Tuesday, June 23rd, 2020
Denise C. Cornelius, Olivia K. Travis, Robert W. Tramel, Marivee Borges-Rodriguez, Cedar H. Baik,Mallory Greer, Chelsea A. Giachelli, Geilda A. Tardo, Jan M. Williams “NLRP3
Renomedullary Interstitial Cell Endothelin A Receptors Regulate BP and Renal Function
Monday, June 8th, 2020
Chunyan Hu, Jayalakshmi Lakshmipathi, Deborah Stuart, Janos Peti-Peterdi, Georgina Gyarmati, Chuan-Ming Hao, Peter Hansell and Donald E. Kohan, “Renomedullary Interstitial Cell Endothelin A Receptors Regulate
The urea transporter UT-A1 plays a predominant role in a urea-dependent urine-concentrating mechanism
Wednesday, June 3rd, 2020
Xiaoqiang Geng, Shun Zhang, Jinzhao He, Ang Ma, Yingjie Li, Min Li, Hong Zhou, Guangping Chen, and Baoxue Yang, “The urea transporter UT-A1 plays a
Revisiting Experimental Models of Diabetic Nephropathy
Tuesday, June 2nd, 2020
Anna Giralt-López, Mireia Molina-Van den Bosch, Ander Vergara, Clara García-Carro, Daniel Seron, Conxita Jacobs-Cachá, and Maria José Soler, “Revisiting Experimental Models of Diabetic Nephropathy,” International
Crystal Clots as Therapeutic Target in Cholesterol Crystal Embolism
Wednesday, May 27th, 2020
Chongxu Shi, Tehyung Kim, Stefanie Steiger, Shrikant R. Mulay, Barbara M. Klinkhammer, Tobias Bäuerle, Maria Elena Melica4,5, Paola Romagnani, Diana Möckel, Maike Baues, Elmina Mammadova-Bach,
Simulated vehicle exhaust exposure (SVEE) in rats impairs renal mitochondrial function
Wednesday, May 27th, 2020
Camila Kochi, Indira Pokkunuri, Ankita Salvi, Mohammad Asghar, Samina Salim, “Simulated vehicle exhaust exposure (SVEE) in rats impairs renal mitochondrial function,” Journal Clinical and Experimental
Metformin Inhibits Cyst Growth and Alters Cell Metabolism in Vitro and Improves Relevant Disease Parameters in a Hypomorphic ADPKD Mouse Model
Friday, May 22nd, 2020
Hui Li, Pei-Yin Ho, Valeria Mancino, Jessica Pham, Saman Sepehr, Biagio Saitta, Nuria M. Pastor-Soler, Kenneth R. Hallows, “Metformin Inhibits Cyst Growth and Alters Cell
Rodent models of diabetic kidney disease: human translatability and preclinical validity
Monday, May 18th, 2020
Frederikke E. Sembach, Mette V. Østergaard, Niels Vrang, Bo Feldt-Rasmussen, Keld Fosgerau, Jacob Jelsing, Lisbeth N. Fink, “Rodent models of diabetic kidney disease: human translatability
Renomedullary Interstitial Cell Endothelin A Receptors Regulated Blood Pressure and Renal Function
Friday, April 24th, 2020
Chunyan Hu, Jayalakshmi Lakshmipathi, Deborah Stuart, Janos Peti-Peterdi, Donald E. Kohan, “Renomedullary Interstitial Cell Endothelin A Receptors Regulated Blood Pressure and Renal Function,” Federation of
Elucidating the Mechanism for Renal Olfactory Receptor 1393’s Attenuated Type 1 Diabetic Phenotype
Friday, April 24th, 2020
Elizabeth G. Considine Alexis R. Schiazza Blythe D. Shepard, “Elucidating the Mechanism for Renal Olfactory Receptor 1393’s Attenuated Type 1 Diabetic Phenotype.” Federation of American
Tempol Improves Renal Autoregulation and Kidney Function Following Ischemia‐Reperfusion Injury in Rats
Friday, April 24th, 2020
Zhengrong Guan, Wenguang Feng, Colton E. Remedies, Bailey A. McEachen, Paul W. Sanders, Edward W. Inscho, “Tempol Improves Renal Autoregulation and Kidney Function Following Ischemia‐Reperfusion
Nephron-Specific Disruption of Polycystin-1 Induces Cyclooxygenase-2–Mediated Blood Pressure Reduction Independent of Cystogenesis
Wednesday, April 22nd, 2020
Jayalakshmi Lakshmipathi, Yang Gao, Chunyan Hu, Deborah Stuart, Jonathan Genzen, Nirupama Ramkumar and Donald E. Kohan, “Nephron-Specific Disruption of Polycystin-1 Induces Cyclooxygenase-2–Mediated Blood Pressure Reduction
Soluble (pro)renin receptor treats metabolic syndrome in mice with diet-induced obesity via interaction with PPARγ
Wednesday, April 15th, 2020
Fei Wang, Renfei Luo, Chang-Jiang Zou, Shiying Xie, Kexin Peng, Long Zhao, Kevin T. Yang, Chuanming Xu, and Tianxin Yang, “Soluble (pro)renin receptor treats metabolic
Renal Fibrosis Is Significantly Attenuated Following Targeted Disruption of Cd40 in Experimental Renal Ischemia
Wednesday, April 8th, 2020
Shungang Zhang, MS; Joshua D. Breidenbach, MS; Fatimah K. Khalaf, MBCHB; Prabhatchandra R. Dube, PhD; Chrysan J. Mohammed, BA; Apurva Lad, MS; Stanislaw Stepkowski, PhD;
Validation of non‐invasive transcutaneous measurement for glomerular filtration rate in lean and obese C57BL/6J mice
Wednesday, April 8th, 2020
Thomas P. Mullins Wei Sheng Tan David A. Carter Linda A. Gallo, “Validation of non‐invasive transcutaneous measurement for glomerular filtration rate in lean and obese
Targeted Inhibition of Gut Microbial TMAO Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease
Wednesday, April 8th, 2020
Nilaksh Gupta, Jennifer A. Buffa, Adam B. Roberts, Naseer Sangwan, Sarah M. Skye, Lin Li, Karen J. Ho, John Varga, Joseph A. DiDonato, W.H. Wilson
Intracellular Reactive Oxygen Species Mediate the Therapeutic Effect of Induced Pluripotent Stem Cells for Acute Kidney Injury
Wednesday, April 8th, 2020
Shun Wang, Xiaoyu Tian, Yijun Li, Rong Xue, Haochen Guan, Meng Lu, Huijun Xu, Zhibin Ye, Sifeng Chen, and Meng Xiang, “Intracellular Reactive Oxygen Species
Impact of choice of kinetic model for the determination of transcutaneous FITC‐sinistrin clearance in rats with streptozotocin‐induced type 1 diabetes
Wednesday, March 18th, 2020
Md Mahbub Ullah, Connie P.C. Ow Roger G. Evans, Lucinda M. Hilliard Krause, “Impact of choice of kinetic model for the determination of transcutaneous FITC‐sinistrin
Liraglutide treatment improves the coronary microcirculation in insulin resistant Zucker obese rats on a high salt diet
Friday, February 28th, 2020
Vijayakumar Sukumaran, Hirotsugu Tsuchimochi, Takashi Sonobe, Mark T. Waddingham, Mikiyasu Shirai and James T. Pearson, “Liraglutide treatment improves the coronary microcirculation in insulin resistant Zucker
Altered renal hemodynamics is associated with glomerular lipid accumulation in obese Dahl salt-sensitive leptin receptor mutant rats
Wednesday, February 26th, 2020
Kasi C McPherson, Corbin A. Shields, Bibek Poudel, Ashley C. Johnson, Lateia Taylor, Cassandra Stubbs, Alyssa Nichols, Denise C. Cornelius, Michael R Garrett, and Jan
α2A-Adrenoceptors Modulate Renal Sympathetic Neurotransmission and Protect against Hypertensive Kidney Disease
Wednesday, February 26th, 2020
Lydia Hering, Masudur Rahman, Henning Hoch, Lajos Markó, Guang Yang, Annika Reil, Mina Yakoub, Vikram Gupta, Sebastian A. Potthoff, Oliver Vonend, Donna L. Ralph, Susan
Hemopexin deficiency promotes acute kidney injury in sickle cell disease
Tuesday, February 18th, 2020
Solomon Ofori-Acquah, Rimi Hazra, Oluwaseun O Orikogbo, Danielle Crosby, Bethany Flage, Ezekiel Bonwin Ackah, Diane Lenhart, Roderick J Tan, Dario A Vitturi, Vivian Paintsil, Ellis