Dynamic changes in the real-time glomerular filtration rate and kidney injury markers in different acute kidney injury models
Wednesday, October 2nd, 2024
Yu Xin, Yanqi Liu, Linqiong Liu, Xinran Wang, Dawei Wang, Yuchen Song, Lifeng Shen, Yuxi Liu, Yuhan Liu, Yahui Peng, Xibo Wang, Yang Zhou, Hongxu
Acute Kidney Injury Results in Long-term Alterations of Kidney Lymphatics in Mice
Wednesday, October 2nd, 2024
Gelare Ghajar-Rahimi,Daria Barwinska, Grace E. Whipple, Malgorzata M. Kamocka, Shehnaz Khan, Seth Winfree, Jennifer LaFontaine, Reham H. Soliman, Arin L Melkonian, Anna A. Zmijewska, Matthew
TRPA1 protects against contrast-induced renal tubular injury by preserving mitochondrial dynamics via the AMPK/DRP1 pathway
Monday, September 16th, 2024
Xinquan Wang, Tao Luo, Yi Yang, Lun Yang, Min Liu, Qingliang Zou, Dan Wang, Changqiang Yang, Qiang Xue, Sen Liu, Jindong Wan, Gaomin He, Anping
Differentiation of crescent-forming kidney progenitor cells into podocytes attenuates severe glomerulonephritis in mice
Monday, August 12th, 2024
Maria Elena Melica1, Giulia Antonelli, Roberto Semeraro, Maria Lucia Angelotti, Gianmarco Lugli, Samuela Landini, Fiammetta Ravaglia, Gilda La Regina, Carolina Conte1, Letizia De Chiara, Anna
Murine kidney transplant outcome is best measured by transdermal glomerular filtration rate
Monday, August 5th, 2024
Collin Z. Jordan, BA, Yanting Chen, PhD, Irma Husain, MBBS, Miriam Dilts, BS, Olivia K. Fay, BS, Jamie Privratsky, MD PhD, Xunrong Luo, MD PhD,
Nanotherapeutic kidney cell-specific targeting to ameliorate acute kidney injury
Monday, July 29th, 2024
Yoshio Funahash, Seung Hun Park, Jessica Hebert, Mahaba B. Eiwaz, Adam C. Munhall, Tahnee Groat, Lingxue Zeng, Jonghan Kim, Hak Soo Choi, “Michael P. Hutchens
DNA-binding protein-A promotes kidney ischemia/reperfusion injury and participates in mitochondrial function
Monday, June 3rd, 2024
Charlotte Reichardt, Sabine Brandt, Anja Bernhardt, Anna Krause, Jonathan A. Lindquist, Sönke Weinert, Robert Geffers, Tobias Franz, Sascha Kahlfuss, Anne Dudeck, Akash Mathew, Rajiv Rana,
Differential Role for the Clock Gene, BMAL1, on Kidney Function in Male versus Female Rats
Thursday, May 30th, 2024
Mary Latimer, Megan Rhoads, Brianna Monroe, Anthony Cook, Edward Inscho, and David Pollock. Physiology Volume 39, Issue S1 2024 May 21, https://doi.org/10.1152/physiol.2024.39.S1.1906
Renal Function and Survival are Reduced in a Polytrauma Acute Radiation Injury Rat Model with Extremity Trauma and Hemorrhage
Thursday, May 30th, 2024
Stephanie Marshall, Luciana Torres, Casey Niland, Jennifer Ybarra, Samandra Demons, and Kathy Ryan, Physiology Volume 39, Issue S1 2024 May 21, https://doi.org/10.1152/physiol.2024.39.S1.916
Podocyte glycocalyx plays an essential role in the function of GFB and the development of albumin leakage
Thursday, May 30th, 2024
Alejandra Becerra Calderon, Audrey Izuhara, Sachin Deepak, Greta Trogen, Solmaz Pourgonabadi, Janos Peti-Peterdi, and Michael Goligorsky. Physiology Volume 39, Issue S1 2024 May 21, https://doi.org/10.1152/physiol.2024.39.S1.1985
Gut microbes regulate glomerular filtration rate in health and in a model of chronic kidney disease
Thursday, May 30th, 2024
Jiaojiao Xu, Eesha Verma, Jason Sanchez, Sepideh Gharaie, Kunal Gupta, Hamid Rabb, and Jennifer L. Pluznick. Physiology Volume 39, Issue S1 2024 May 21, https://doi.org/10.1152/physiol.2024.39.S1.603
Alleviating renal injury and mitochondrial dysfunction following hemorrhagic shock
Thursday, May 30th, 2024
Cianna Kennard, Alfredo Calderon, Harold Klemcke, Kennedy Mdaki, Stephanie Marshall, Michael Meledeo, and Lusha Xiang. Physiology Volume 39, Issue S1 2024 May 21, https://doi.org/10.1152/physiol.2024.39.S1.847
Time-Dependent Regulation of Cystogenesis and Disease Severity by AMPK in Polycystic Kidney Disease Cells and Mice
Thursday, May 30th, 2024
Kenneth Hallows, Hui Li, Jessica Pham, Saman Sepehr, Kayvon Solaimanpour, Yu-Wei Chen, and Valeria Mancino. Physiology Volume 39, Issue S1 2024 May 21, https://doi.org/10.1152/physiol.2024.39.S1.1042
The role of CCN1 in kidney-brain crosstalk
Thursday, May 30th, 2024
Anna Peti-Peterdi, Lena Peresztegi, Alejandra Becerra Calderon, Audrey Izuhara, Sachin Deepak, Georgina Gyarmati, and Janos Peti-Peterdi. Physiology Volume 39, Issue S1 2024 May 21, https://doi.org/10.1152/physiol.2024.39.S1.1968
All-trans retinoic acid pretreatment of mesenchymal stem cells enhances the therapeutic effect on acute kidney injury
Thursday, May 30th, 2024
Yifan Zhang, Xiaochen Wang, Yuwei Ji, Haijuan Hong, Xiaodong Geng, Keying Zhang, Zhangning Fu, Guangyan Cai, Xiangmei Chen, Ping Li and Quan Hong, “All-trans retinoic
All-trans retinoic acid enhances the efficacy of mesenchymal stem cells in acute kidney injury
Tuesday, May 28th, 2024
Yifan Zhang, Xiaodong Geng, Yuwei Ji, Xiaocheng Wang, Keying Zhang, Guang-Yan Cai, Xiangmei Chen, Quan Hong, “All-trans retinoic acid enhances the efficacy of mesenchymal stem
Combination therapy with Lisinopril and Dapagliflozin rescues GFR decline and glomerular damage in the KKAy mouse model of diabetic kidney disease
Tuesday, May 28th, 2024
Arianne van Koppen, Simon Hinke, Tri Nguyen, Amélie Dendooven, Tzu-Ling Tseng, Wei-Chan Hsu, Ingeborg Bajema, Aswin Menke, Harry van Goor, Reinout Stoop, “Combination therapy with
Rosmarinic acid plus deferasirox inhibits ferroptosis to alleviate crush syndrome-related AKI via Nrf2/Keap1 pathway
Friday, May 10th, 2024
Ou Qiao, Li Zhang, Lu Han, Xinyue Wang, Zizheng Li, Fengjiao Bao, Herui Hao, Yingjie Hou, Xiaohong Duan, Ning Li, Yanhua Gong, “Rosmarinic acid plus
Neuronally differentiated macula densa cells regulate tissue remodeling and regeneration in the kidney
Monday, April 29th, 2024
Georgina Gyarmati, Urvi Nikhil Shroff, Anne Riquier-Brison, Dorinne Desposito, Wenjun Ju, Sean D. Stocker, Audrey Izuhara, Sachin Deepak, Alejandra Becerra Calderon, James L. Burford, Hiroyuki
Direct mapping of kidney function by DCE-MRI urography using a tetrazinanone organic radical contrast agent
Monday, April 8th, 2024
Nicholas D. Calvert, Alexia Kirby, Mojmír Suchý, Peter Pallister, Aidan A. Torrens, Dylan Burger, Gerd Melkus, Nicola Schieda & Adam J. Shuhendler, “Direct mapping of
Tubular CPT1A deletion minimally affects aging and chronic kidney injury
Monday, March 25th, 2024
Safaa Hammoud, Alla Ivanova, Yosuke Osaki, Steven Funk, Haichun Yang, Olga Viquez, Rachel Delgado, Dongliang Lu, Melanie Phillips Mignemi, Jane Tonello, Selene Colon, Louise Lantier,
Nascent shifts in renal cellular metabolism, structure, and function due to chronic empagliflozin in pre-diabetic mice
Tuesday, March 12th, 2024
Blythe D. Shepard, Jennifer Chau, Ryan Kurtz, Avi Z Rosenberg, Pinaki Sarder, Samuel P Border, Brandon Ginley, Olga Rodriguez, Chris Albanese,Grace Knoer, Aarenee Greene, Aline
Cognate antigen-independent differentiation of resident memory T cells in chronic kidney disease
Tuesday, March 12th, 2024
Kyle H. Moore, Elise N. Erman, Amie M. Traylor, Stephanie K. Esman, Yanlin Jiang, Jennifer R. LaFontaine, Anna Zmijewska, Yan Lu, Reham H. Soliman, Anupam
Proteomic analyses of urinary exosomes identify novel potential biomarkers for early diagnosis of sickle cell nephropathy, a sex-based study
Monday, March 4th, 2024
Balamurugan Packialakshmi, Emily Limerick, Hans C. Ackerman, Xionghao Lin, Sergei Nekhai, James D. Oliver III, Ian J. Stewart, Mark A. Knepper, Courtney Fitzhugh and Xiaoming
Acute and Chronic Kidney Disease Worsen Outcomes in Experimental Sepsis
Friday, March 1st, 2024
Floyd, Deana F., Colbert, James F., Feng, Frances, Furgeson, Seth B., Montford, John R.,”Acute and Chronic Kidney Disease Worsen Outcomes in Experimental Sepsis”, Kidney360, February
Comparative Analysis of Acute Kidney Injury Models and Related Fibrogenic Responses: Convergence on Methylation Patterns Regulated by Cold Shock Protein
Monday, February 26th, 2024
Sabine Brandt, Anja Bernhardt, Saskia Häberer, Katharina Wolters, Fabian Gehringer, Charlotte Reichardt, Anna Krause, Robert Geffers, Sascha Kahlfuß, Andreas Jeron, Dunja Bruder, Jonathan A. Lindquist,
Neuropilin-1 regulates renin synthesis in juxtaglomerular cells
Monday, February 26th, 2024
Yunzhu Shen, Kenza Lotenberg, Jeremy Zaworski, Katharina A.-E.Broeker, Florence Vasseur, Liliane Louedec, Sandrine Placier, Perrine Frère, Marie-Christine Verpont, Pierre Galichon, David Buob, Juliette Hadchouel, Fabiola
Short-term hypercaloric carbohydrate loading increases surgical stress resilience by inducing FGF21
Friday, February 9th, 2024
Thomas Agius, Raffaella Emsley, Arnaud Lyon, Michael R. MacArthur, Kevin Kiesworo, Anna Faivre, Louis Stavart, Martine Lambelet, David Legouis, Sophie de Seigneux, Déla Golshayan, Francois
A heart derived-soluble factor which controls kidney and cardiovascular function after acute cardiorenal syndrome
Monday, January 29th, 2024
Michael Hutchens, Yoshio Funahashi, Jessica Hebert, Adam Munhall, Kevin Burfeind, Elizabeth Nguyen, Tahnee Groat, Megan Nickerson1, Mahaba Eiwaz, Nicole Andeen, Motoko Yanagita, Susan Gurley, “A
A stable liver-specific urate oxidase gene knockout hyperuricemia mouse model finds activated hepatic de novo purine biosynthesis and urate nephropathy
Monday, January 22nd, 2024
Lei Pang, Ningning Liang, Changgui Li, Tony R. Merriman, Hui Zhang, Fei Yan, Wenyan Sun, Rui Li, Xiaomei Xue, Zhen Liu, Can Wang, Xiaoyu Cheng,
A model of hemodialysis after acute kidney injury in rats
Tuesday, December 26th, 2023
J. Mallet1, P.‑A. Billiet, M. Scarton1, N. Benichou, M. Bobot, K. Chaibi, A. Hertig, J. Hadchouel, D. Dreyfuss, S. Gaudry, and S. Placier, “A model
Combining renin-angiotensin system blockade and sodium-glucose cotransporter-2 inhibition in experimental diabetes results in synergistic beneficial effects
Friday, December 15th, 2023
Edwyn O Cruz-López, Dien Ye, Daniel G Stolk, Marian C Clahsen-van Groningen, Richard van Veghel, Ingrid M Garrelds, Marko Poglitsch, Oliver Domenig, Rahi S Alipour
Abcc6 deficiency prevents rhabdomyolysis-induced acute kidney injury
Tuesday, December 12th, 2023
Audrey Casemayou, Julie Belliere, Emmanuel Letavernier, Eloïse Colliou, Hélène El Hachem, Jeremy Zarowski, Dominique Bazin, Clément Kounde, Alexis Piedrafita, Guylène Feuillet, Joost P. Schanstra &
Cyclooxygenase-2 inhibition prevents renal toxicity but not hypertension during sunitinib treatment
Thursday, November 30th, 2023
Daan C.H. van Dorst, Katrina M. Mirabito Colafella, Richard van Veghel, Ingrid M. Garrelds, René de Vries, Ron H.J. Mathijssen, A.H. Jan Danser, Jorie Versmissen,
Legal Performance-enhancing Drugs Alter Course and Treatment of Rhabdomyolysis-induced Acute Kidney Injury
Monday, November 13th, 2023
Jessica F Hebert, Mahaba B Eiwaz, Megan N Nickerson, Adam C Munhall, Akash A Pai, Tahnee Groat, Nicole K Andeen, Michael P Hutchens, “Legal Performance-enhancing
Combination Therapy with Lisinopril and Dapagliflozin Rescues GFR Decline and Glomerular Damage in the KKAy Mouse Model of Diabetic Kidney Disease
Friday, November 10th, 2023
Arianne Van Koppen, Andrea R. Nawrocki, Simon A. Hinke, Harry van Goor, Ingeborg M. Bajema, Amélie Dendooven, Tri Q. Nguyen, Matthew D. Breyer, Reinout Stoop.
Preclinical Models of AKI
Friday, November 10th, 2023
Manjula Darshi, Rong Meng, Eugene Myshkin, Raul Camacho, Fuyong Du, Li-Jun Ma, George Ho, Jianying Liu, Qiu Li, Kamal A. Albarazanji, JeramieWatrous, Tao Long, Mo
AKI Results in Sustained, Long-Term Alterations of Kidney Lymphatics
Friday, November 10th, 2023
Gelare Ghajar-Rahimi, Daria Barwinska, Grace Whipple, Malgorzata Kamocka, Shehnaz Khan, SethWinfree, James F. George, Tarek M. El-Achkar, Anupam Agarwal. ASN Abstract supplement J Am Soc
Differential Renal Responses to Dexamethasone in Rats and Mice Following AKI
Friday, November 10th, 2023
Henriette Frikke-Schmidt, Stephen Beck, Meghan M. Pryor, Rong Meng, Joseph Strizziere, Matthew M. Rankin, Lili Guo, Fuyong Du, Shefali Patel, Andrea R. Nawrocki, Jan M.
A Novel RIPK3/BRD4 Small Molecule Inhibits Arsenical-Induced AKI
Friday, November 10th, 2023
Arin Melkonian, Kyle H. Moore, Amie Traylor, Laurence M. Black, Anna A. Zmijewska, Stephanie Esman, Ritesh Srivastava, Mohammad Athar, James F. George, Anupam Agarwal. ASN
The Adenine-Induced Mouse Model of CKD Shows Rapid Development of Impaired Kidney Function, Renal Fibrosis, Muscle Wasting, and Anemia
Friday, November 10th, 2023
Maria K. Ougaard, Frederikke E. Sembach, Jacob Nøhr-Meldgaard, Adam B. Marstrand-Jørgensen, Henrik H. Hansen, Michael Christensen. ASN Abstract supplement J Am Soc Nephrol 34: 2023
Targeting Interleukin-6/Glycoprotein130 Signaling Ameliorates Renal Injury in Polycystic Ovary Syndrome
Friday, November 10th, 2023
Samar Rezq, Jelina Basnet, Alexandra M. Huffman, Joseph R. Flaherty, Ahmed Abdelhameed, Amira E. Alsemeh, Tolulope E. Asala,1 Licy Yanes Cardozo, Damian G. Romero. ASN
AMPK Activation Protects Kidney Function After Renal Ischemia Reperfusion Injury in Rats
Friday, November 10th, 2023
Henriette Frikke-Schmidt, Kamal A. Albarazanji, Jenson Qi, David Frederick, Fuyong Du, Rong Meng, George Ho, Andrea R. Nawrocki, Alessandro Pocai. ASN Abstract supplement J Am
Ketogenic Diet Mitigates Renal Fibrosis and Partially Preserves Kidney Function in Nephrotoxic Serum Nephritis
Friday, November 10th, 2023
Konstantin A. Kloetzer, Max Schuller, Marcell Krall, Katharina Artinger, Corinna Schabhüttl, Agnes A. Mooslechner, Hansjörg Habisch, Tobias Madl, Alexander R. Rosenkranz, Philipp Eller, Kathrin Eller.
The Kidney-Gut-Brain Axi
Friday, November 10th, 2023
Jihyun Yang, Young Eun Choi, Sungyeon Kim, Suk Min Chung, Yookyung Jang, Ko Yoon Sook, Lee Hee Young, Tai yeon Koo, Sewon Oh, Myung-Gyu Kim,
Prevention of Ischemia-Reperfusion Injury (IRI)-Induced AKI by Maintaining Na+/K+ ATPase Activity
Friday, November 10th, 2023
Nadezhda N. Zheleznova, Tamara A.Wahbeh, Lei Wang, Jie Zhang, JinWei, Nathan Hall, Nohely Hernandez Soto, Bo Chen, Wei Chen, Ruisheng Liu. ASN Abstract supplement J
The SGLT2 inhibitor dapagliflozin improves kidney function in glycogen storage disease XI
Monday, November 6th, 2023
Francesco Trepiccione, Anna Iervolino, Mariavittoria D’Acierno, Sabrina Siccardi, Vincenzo Costanzo, Donato Sardella, Luigi R. De La Motte, Luciano D’Apolito, Antonio Miele, Alessandra F. Perna, Giovanna
Chronic intermittent hypoxia promotes glomerular hyperfiltration and potentiates hypoxia-evoked decreases in renal perfusion and PO2
Tuesday, October 10th, 2023
Kiefer W. Kious, Kalie A. Savage, Stephanie C. E. Twohey, Aubrey F. Highum1, Andrew Philipose, Hugo S. Díaz, Rodrigo Del Rio, James A. Lang, Sarah
Kidney functional reserve, KFR, and damage biomarkers in subclinical chronic kidney disease complicated by acute kidney injury
Tuesday, September 26th, 2023
Kylie M Taylor, Amy Ym Au, Sanjeeva Herath, Lena Succar, Jasmine Wong, Jonathan Erlich, Zoltan H Endre, “Kidney functional reserve, KFR, and damage biomarkers in
Inhibition of retinoic acid signaling in proximal tubular epithelial cells protects against acute kidney injury
Monday, September 18th, 2023
Min Yang, Lauren N. Lopez, Maya Brewer, Rachel Delgado, Anna Menshikh, Kelly Clouthier, Yuantee Zhu, Thitinee Vanichapol, Haichun Yang, Raymond C. Harris, Leslie Gewin, Craig
Female but Not Male Mice Deficient in Soluble IgM Are Susceptible to Chemically Induced Glomerular Injury
Friday, September 15th, 2023
Russell Whelan, Andrew Feemster, Jennifer Laskowski, Brandon Renner, Liudmila Kulik, Felix Poppelaars, Cameron Lee, V. Michael Holers, Joshua M. Thurman, “Female but Not Male Mice
IL-6 mediates the hepatic acute phase response after prerenal azotemia in a clinically-defined murine model
Tuesday, July 25th, 2023
Kayo Okamura, Sizhao Lu, Zhibin He, Chris Altmann, John R. Montford, Amy Li, M. Scott Lucia, David J. Orlicky, Mary Weiser-Evans, and Sarah Faubel, “IL-6
